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PHARMACOLOGY NR566 FINAL EXAM QUESTIONS WITH COMPLETE SOLUTIONS
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PHARMACOLOGY NR566 FINAL EXAM QUESTIONS WITH COMPLETE SOLUTIONS
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PHARMACOLOGY NR566 FINAL EXAMQUESTIONS WITH COMPLETE
SOLUTIONS
For treatment of existing osteoporosis, the dose of alendronate - Answer-10 mg/day or
70 mg/week
Initial dosage for bone less prevention alendronate and risedronate - Answer-5 mg/day
or 35 mg/week
For treatment of existing osteoporosis, the dose of risedronate - Answer-75 mg for 2
consecutive days or 150 mg once a month
Alendronate (Fosamax) - Answer-Therapy with 10 mg daily can increase bone density
by up to 10% after 3 years and can decrease vertebral and hip fractures by 50%
Testosterone replacement therapy - Answer-risk of prostate cancer
Testosterone replacement therapy - Answer-Erythrocytosis is a risk; Hgb and Hct levels
checked, expect increase first 6 mths, unless Hgb level higher than 17.5 g/dL, Hct
higher than 54%, or both suggests overtreatment or occasionally abuse. IM happens
more than transdermal. If the Hct is greater than 54%, therapy is stopped until the Hct
decreases to a safe level. The patient should also be evaluated for hypoxia and sleep
apnea. Restarting therapy at a reduced dose usually solves problems.
Adults with vitamin B12 deficiency that is not pernicious anemia - Answer-1,000 mcg of
oral cobalamin are given until normal B12 levels are achieved—usually 6 to 12 weeks.
In seriously ill patients, both vitamin B12 and folic acid may need to be administered.
Who cannot get TRT - Answer-breast cancer in a male patient, prostrate cancer,
polycythemia vera, increased calcium in the blood from cancer, diabetes, high
cholesterol, overweight and high blood pressure
BC contraindications - Answer-Age >40 yr or Smoker <35 yr
BMI >30 due to increased VTE risk
HTN or hyperlipidemia
First-degree relative with DVT/PE
Major surgery without prolonged immobilization
Superficial thrombophlebitis
SLE on immunosuppressive therapy or with severe thrombocytopenia
Rheumatoid arthritis Sickle cell disease
BC contraindications - Answer-Valvular heart disease, uncomplicated
, Migraine without neurological aura, age <35 yr
Unexplained vaginal bleeding, suspicious for serious underlying condition
Cervical intraepithelial neoplasia
Cervical cancer, awaiting treatment
Undiagnosed breast mass
BC contraindications - Answer-Diabetes, insulin dependent or non-insulin-dependent,
without vascular disease
Asymptomatic gallbladder disease or postcholecystectomy
Benign focal nodular hyperplasia of the liver
Hx of cholestasis in pregnancy
Ulcerative colitis or Crohn's disease
Postpartum & breastfeeding
ethinyl estradiol/norgestimate contraindications - Answer-Current or prior history of an
estrogen-dependent cancer
Pregnancy
Undiagnosed dysfunctional uterine bleeding
DVT
Arterial thromboemboli within the prior year
Clotting disorders
Severe hepatic disease.
Estrogens in pregnancy - Answer-Category X due to high rate of teratogenicity in male
and female offspring
Syhpilis treatment (early/primary/secondary) - Answer-1. Pen G 2.4m IM (adults),
50,000u/kg (kids)
2. doxycycline 100mg BID 14d
3. Tetracycline 500mg QID 14d
Syhpilis treatment (later) - Answer-Pen G 2.4m IM (adults) weekly x 3 weeks
Gonorrhea treatment - Answer-1. Rocephin 250mg IM w/ Zithro 1000mg po
2. Rocephin 250mg IM w/ doxycycline 100mg BID 7d
3. Zithro 2g PO
Chlamydia treatment - Answer-1. Zithro 1G PO
2. Doxycycline 100mg BID 7d
3. Erythromycin 500mg QID 7d
chancroid tx - Answer-1. Zithro 1G po/Rocephin 250mg IM
Herpes treatment 1 and 2 - Answer-acyclovir 400mg TID 7-10d
HPV tx - Answer-podofilox 0.5% topically BID 3d
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