MB(ASCP) Genes, Drugs, and Translocations exam with 100% correct answers
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MB Genes, Drugs, and Translocations
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MB Genes, Drugs, And Translocations
Mutation in UGT1A1 affects metabolism of what drug? correct answersIrinotecan
What genes would be screened in a breast cancer panel? correct answersHER2, ERBB2, BRCA1
What is the most common mutation in Hemochromatosis? correct answersC282Y
Testing for HOXB13, BRCA1 and BRCA2 is usually do...
Mutation in UGT1A1 affects metabolism of what drug? correct answersIrinotecan
What genes would be screened in a breast cancer panel? correct answersHER2, ERBB2, BRCA1
What is the most common mutation in Hemochromatosis? correct answersC282Y
Testing for HOXB13, BRCA1 and BRCA2 is usually done in patients with: correct answersProstate cancer
In CML, what fusion protein is created? correct answersBCR-ABL1
Mantle cell lymphoma (MCL) is caused by what translocation? correct answerst(11;14)
Which two HPV types are responsible for most cases of cervical cancer? correct answers16 and 18
Acute promyelocytic leukemia (APL) is responsible for what translocation? correct answerst(15;17)
All of the following are trinucleotide repeat disorders, EXCEPT: correct answersAsperger Disease
The mother of a 3 year old boy took him to the doctor's office for concerns of an underlying genetic
condition. A karyotype order was sent to the Molecular Diagnostic lab. Karyotype results show 47, XY,
+21. Based on these results, the boy has: correct answersDown Syndrome
What translocation is associated with Burkitt's lymphoma? correct answerst(8;14)
T-Cell Gene Rearrangement is seen in what malignancy? correct answersNon-Hodgkin Lymphoma
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