VUSN Pharmacology Exam 2 (Week Ten)
intolerance to cold, receding hairline, hair loss, facial and eyelid edema, dull-blank expression, extreme
fatigue, thigh tongue - slow speech, apathy, dry skin (coarse and scaly), muscle aches and weakness,
constipation, anorexia, brittle nails and hair, menstrual disturbances - symptoms of
hypothyroidism
pituitary gland - which gland controls the thyroid?
pituitary gland -> thyroid -> stimulating hormone -> thyroid -> thyroxine - pathway of pituitary to
thyroid
levothyroxine, propylthiouracil, somatropin, desmopressin, fludrocortisone - endocrine prototype
drug list
pituitary, thyroid, parathyroid, pancreas, testes, ovaries - endocrine glands
oxytocin, antidiuretic hormone - posterior pituitary hormones
GH, ACTH, TSH, FSH, LH, prolactin - anterior pituitary hormones
GnRH, GHRH, PRF, CRH, TRH, somatostatin, dopamine - hypothalamic releasing factors
low thyroxine levels - what causes pituitary gland to secrete thyroid-stimulating hormone?
thyroxine - thyroid secretes what?
thyroid-stimulating hormone - pituitary gland secretes what? (in relation to thyroid)
, 99.5% protein bound - why is metabolism of T4 so slow?
T3 - what is T4 converted to?
hypothyroidism - if thyroid is not functioning correctly it won't produce enough T4, pituitary gland
will notice and keep creating excessive thyroid-stimulating hormone
T4 - another name for thyroxine
thyroid-stimulating hormone - T4 has inverse relationship with which hormone?
pituitary gland - in hyper and hypothyroidism, which organ is still functioning correctly?
hyperthyroidism - thyroid is producing excessive T4, pituitary gland notices excess and decreases
production of thyroid-stimulating, leading to less production of T4
high T4, low TSH - hormone levels in hyperthyroidism
low T3 and T4, high TSH - hormone levels in hypothyroidism
free T4 - measure of T4 that is not protein bound
T4 thyroid function test - measures total OR free levels of T4
free T4 thyroid function test - only measures free T4
T3 thyroid function test - measures total amount of T3
TSH thyroid function test - measures total amount of TSH