Exam (elaborations)
ALLERGY TESTING AND IMMUNOTHERAPY QUESTIONS AND ANSWERS WITH SOLUTIONS 2024
- Course
- Institution
ALLERGY TESTING AND IMMUNOTHERAPY QUESTIONS AND ANSWERS WITH SOLUTIONS 2024
[Show more]
Content preview
ALLERGY TESTING ANDIMMUNOTHERAPY QUESTIONS AND
ANSWERS WITH SOLUTIONS 2024
what're the most common allergens? - ANSWER -pollens
-fungal spores
-house-dust mites, roaches
-animal materials
-insect venoms
-drugs
-latex
-foods
what does a positive allergy test document? - ANSWER *presence of allergen-specific IgE antibody*
dg of allergy can be made only by correlating testing results w the presence of clinical symptoms
what're the indications to undergo allergy testing? - ANSWER -allergic rhinitis
-allergic conjunctivitis
-asthma
-anaphylaxis to: aeroallergens, foods, insect venoms, drugs
how do we do allergy testing (broadly)? - ANSWER *skin testing:*
-skin prick test
-intradermal test
*IgE RAST/ImmunoCAP*
what does allergy skin testing exclude or confirm? - ANSWER IgE-mediated disease
, attempts to detect the presence of allergen-specific IgE bound to mast cells by eliciting mast cell
degranulation to the specific allergen being tested
what's the allergic cascade? - ANSWER -IgE recognizes antigen
-protmotes degranulation of mast cell
-release of histamine
-->stimulates nerve endings to cause itching (3-5 min)
-->causes vasodilation to cause redness (5-10 min)
-release of other mediators: prostaglandins, tryptase, heparin
-->endothelial gaping/fluid leakage causes swelling
what causes itching, redness and swelling in allergic reaction? when do these occur? - ANSWER itching =
histamine, in 3-5 min
redness = vasodilation by histamine, in 5-10 min
swelling = endothelial gaping/fluid leakage from prostaglandins, tryptase, heparin
how does RAST goes? - ANSWER -antigen (allergin)
- allergen specific IgE in serum binds
-radioactivity labelled anti-IgE lights up
how does ImmunoCAP work? - ANSWER -IgE specific antibody binds to antigens
-add substance that attaches to enzymes
-those light up
*quantified test*
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Performance. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $15.49. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
79064 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now