NR 566 MIDTERM STUDY GUIDE
QUESTIONS AND ANSWERS WITH
SOLUTIONS 2024
Common CAP pathogens - ANSWER S. Pneumoniae (most common)
H. Influenzae (smokers/COPD)
P. Aeruginosa (CF)
CAP first line treatment - ANSWER Macrolides, Doxycyline, Amoxicillin
what to give if 1st CAP treatment doesn't work? - ANSWER Respiratory Fluoroquinolone if not received
abx in the past 3 months
Mycoplasma pneumoniae - ANSWER atypical pneumonia; commonly seen in children
pediatric atypical pneumonia treatment - ANSWER Macrolides (Erythromycin), if failed then Respiratory
fluoroquinolone
CAP treatment during pregnancy - ANSWER Amoxicillin, cephalosporins, or Erythromycin
Treatment of chlamydial pneumonia in infant - ANSWER Macrolide (Azithromycin): 500mg orally on day 1
followed by 250 mg once daily on days 2-5
When to use broad/empiric spectrum antibiotics? - ANSWER Before cultures are resulted/ critically ill
patient after first culture obtained, based on NP knowledge of patient history, local
susceptibility/geographic location
When to use narrow spectrum antibiotics? - ANSWER Used when the culture and sensitivity is resulted,
and pathogen is known.
how to treat C.diff - ANSWER Stop the antibiotic that may have caused it
1st: Vancomycin 125 mg PO QID x 10 days.
2nd: Metronidazole 500mg PO TID x 10 days
address hydration
Drug class known for ALL drugs in class to promote development of C. Diff - ANSWER 2nd and 3rd
generation Cephalosporins
Penicillin: Cross-sensitivity reactions with which drug classes - ANSWER Cephalosporins & Carbapenems
(Allergy may be mild or severe)
Safe penicillin during pregancy - ANSWER Amoxicillin
, patient education for Cephalosporins - ANSWER Report to provider any loose stools, complete full course
of antibiotics, s/s of allergy
Cephalosporins in pregnancy - ANSWER All appear safe for use
patient education for Tetracyclines - ANSWER photosensitivity (wear sunscreen!), complete full course,
s/s of allergy
Tetracyclines in pregnancy - ANSWER Can lead to fetal death; avoided for use
Patient education for macrolides - ANSWER Take with meals to avoid GI upset, contraindicated w/
warfarin
Aminoglycoside patient teaching - ANSWER Patients should report tinnitus, high-frequency hearing loss,
persistent headache, nausea, dizziness or vertigo
sulfonamides patient teaching - ANSWER Finish full course
Increase fluid intake to 8-10 cups/day
Take on empty stomach
Avoid sun exposure/wear sunscreen
Sulfonamides during pregnancy - ANSWER not to be used during 1st trimester, can cause kernicterus in
infants
Risks associated with Saquinavir - ANSWER cardiac dysrhythmia, heart failure
PR Interval impacts use of which HIV drugs? - ANSWER Protease inhibitors: Saquinavir, Atazanavir,
Lopinavir, Ritonavir
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