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HAZWOPER 40 - Lesson 3 - Toxicology
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HAZWOPER 40 - Lesson 3 - Toxicology
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HAZWOPER 40 - Lesson 3 -Toxicology
Chemicals in combination can produce different biological responses than
the responses seen when exposure is to one chemical alone.
True
False - -True
-________ is the most common route of exposure leading to a toxic dose in
the work environment
Injection
Ingestion
Inhalation
Eye/Skin contact - -
-LD 50 of 25 mg/m3 means that a concentration of 25 mg/m3 of a certain
substance indicates:
50 people out of a group of 80 exposed to a concentration 25 mg/m3 of a
substance were shown to have experienced a fatal dose.
50% of the concentration of a substance cause fatality in those be exposed.
A concentration of 25 mg/m3 of a substance is shown to have been fatal to
50 percent of a test group of animals.
LD 50 is a fictitious term and does not indicate anything. - -A concentration
of 25 mg/m3 of a substance is shown to have been fatal to 50 percent of a
test group of animals.
-Factors affecting response to chemical exposure include:
Toxicity
Route of exposure
Chemical dose
All of the above - -All of the above
-________ provide most of what we know about the dangerous effects of toxic
substances.
Epidemiological studies
Animal studies
Estimation studies
, Actual exposures to a chemical in the workplace - -Epidemiological studies
Animal studies
-Example of chemical ________ are carbon monoxide and hydrogen cyanide.
Hepatoxins
Hematoxins
Asphyxiants
Nephrotoxins - -Asphyxiants
-The ACGIH publication: ________ for Chemical Substances and Physical
Agents, OSHA standard 29 CFR part 1910.1000, and other standards
reference identify substances that can be readily absorbed through the skin,
mucous membranes, and/or eyes by either airborne exposures or direct
contact with a liquid.
Threshold Limit Values
HAZCOM
Right-to-know
SDS - -Threshold Limit Values
-Polyurethane foam, when burnt, gives off:
Sulfuric acid
Cyanide gas
Ethane
Phosphine - -Cyanide gas
-Animal studies provide most of what we know about the dangerous effects
of toxic substances. Humans may react differently than animals exposed to
toxic materials.
False
True - -True
-A(n) ________ is the airborne concentration of a material to which nearly all
individuals may be repeatedly expose without adverse health effects.
Chemical exposure
Sensitizer threshold
Exposure limit
Irritant level - -Exposure limit
-When a chemical with no known toxic effects acts together with a known
toxic substance to make the combined toxic substance even more potent,
this is called ________ interaction.
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