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Nurs 208 Drugs for Peptic Ulcer Disease and GERD Notes

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This is a comprehensive and detailed note on Drugs for Peptic Ulcer Disease and GERD for Nurs 208. * Essential!! * For you!!

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  • August 19, 2024
  • 18
  • 2018/2019
  • Class notes
  • Prof. lisa
  • All classes

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Drugs for Peptic Ulcer
Disease and GERD




Peptic Ulcer Disease
Peptic Ulcer Disease (continued)…
• Lesion in stomach called gastric ulcer • Heliocobacter pylori (H. pylori)

• Lesion in small intestine called duodenal ulcer Primary cause of peptic ulcers

• Associated with several risk factors Gram-negative bacterium

• Other causes (contributors to ulcers and inflammation)
Family history, type O blood
Secretion of excess gastric acid
Tobacco use and caffeine
Hypo secretion of adequate mucus
Glucocorticoids and NSAIDs

, NSAIDs (most common cause in those that are not
Psychological stress infected with H. pylori)

, Gastroesophageal Reflux Gastroesophageal Reflux
Disease disease (continued)…
• Acidic stomach contents move up into esophagus
• Caused by loosening of the sphincter
between esophagus and stomach Causes intense burning (heartburn)

May lead to esophageal ulcers, esophagitis, or
strictures
• Associated with obesity
• Lifestyle changes can improve GERD symptoms




Treatment of Gastroesophageal Treatment of Peptic Ulcer
Reflux Disease (continued)… Disease
• Combination of lifestyle changes and
• Drug classes
pharmacotherapy best
H2 receptor blockers
• Treatment goals
Antacids Eliminate infection by H. pylori
Proton pump inhibitors Promote ulcer healing

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