Exam (elaborations)
PHM 350 Exam 1 | 450 Questions | With Complete Solutions
- Course
- Institution
PHM 350 Exam 1 | 450 Questions | With Complete Solutions
[Show more]
Content preview
PHM 350 Exam 1 | 450 Questions | With Complete Solutions(skeletal muscle) neuromuscular junctions Correct Answers all
the junctions between somatic motor neurons and skeletal
muscle
[A-] Correct Answers concentration of ionized (non-
protonated) acid
[B] Correct Answers concentration of non-ionized (non-
protonated) base
[BH+] Correct Answers concentration of ionized (protonated)
base
[HA] Correct Answers concentration of non-ionized
(protonated) acid
2 types of cholinergic receptors Correct Answers muscarinic
nicotinic
3 outputs from the spinal cord Correct Answers ANS - SNS
ANS - PNS
Somatic
5 drug movement mechanisms Correct Answers bulk flow
transporter
,endocytosis
exocytosis
diffusion
a drug does not have a single effect because Correct Answers a
drug interacts with multiple types of receptor
a drug interacts with a single type of receptor located on
different cell types coupled to multiple response mechanisms
a drug with a high TI and SSM may have Correct Answers
high or low therapeutic potency
a drug with high therapeutic potency may have high or low
Correct Answers TI and SSM
a drug with low therapeutic potency may have a Correct
Answers high or low TI and SSM
a drug with low TI and SSM may have Correct Answers high
or low therapeutic potency
a measure of drug safety (TI) can measure the Correct Answers
ED50
a non-ionized drug will diffuse across the membranes into the
other chamber until Correct Answers equilibrium
,absorption Correct Answers important processes from getting a
drug from any space or compartment in the body to any other
space
acetylcholine activates __________ receptors Correct Answers
N and M cholinergic receptors
acetylcholine has the same affinity for Correct Answers
nicotinic and muscarinic receptors
acetylcholine is a Correct Answers choline ester so it is
possible that we could change it a little bit to enhance its ability
to be absorbed and to enhance the possibility that it will not be
metabolized so quickly so it would stay in the blood for a
sufficient time and have effects
acetylcholine is a _______ molecule Correct Answers charged
(if you put it in the gut it doesn't get into the blood very fast)
not absorbed through the GI tract or mucosa
does not enter the CNS
acetylcholine is metabolized by Correct Answers
acetylcholinesterase at all cholinergic synapses (this enzyme is
very fast at this but not good at metabolizing any other choline
ester)
acetylcholine is metabolized by nonspecific cholinesterase in the
Correct Answers plasma (without it you get acetylcholine
staying in the synapse)
, acetylcholine is not absorbed across Correct Answers mucosa
or GI tract
does not enter the central nervous system
acetylcholine is present anywhere there is a Correct Answers
cholinergic synapse
ACh degradation causes the production of Correct Answers
choline
ACh esterase Correct Answers enzyme that metabolizes ACh
ACh is a substrate for Correct Answers AChEase and ChEases
ACh is equally good for both
it terminates ACh action at cholinergic synapses
other choline esters are also substrates for ChEases but not
AChEase
ACh is proven to be an Correct Answers agonist
ACh is very rapidly metabolized by Correct Answers
ACHEase and ChEases in plasma
adjunct to ECT Correct Answers help with the symptoms of
electroconvulsive shock treatment
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Classroom. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $17.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
79373 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now