PHM 321 exam 1 Questions With Complete Solutions
2 classes of drugs for flu Correct Answers tricylic amines
sialic acid analogs
2 mechanisms of GI irritation form NSAIDS Correct Answers -
direct irritation (aspirin)
-decreases mucous coating in stomach lining (mucous
production is regulated by prostaglandins)
3 factors that make up a drug Correct Answers 1. exogenous
substance
2. alters biochem or physiology
3. produces and effect
3 major drug classes for asthma Correct Answers
corticosteroids, anti-leukotrienes, and long-acting B2 agonists
3 major physiological function of histamine Correct Answers
immune response, neurotransmitter in CNS, regulation of GI
function
3 primary effects of NSAIDS Correct Answers reduce pain
(analgesic)
reduce fever (antipyretic)
reduce inflammation
3 signs of neuropathic pain Correct Answers hypersensitivity to
painful stimuli, spontaneous pain, and allodynia
,3 types of flu vaccines Correct Answers inactivated, live
attenuated, and recombinant (no actual virus, egg-free)
absorption of ethanol Correct Answers rapid, in the intestine,
slowed by food, max concentration after 30 mins
-crosses BBB and placenta
Acetaminophen Correct Answers -less irritating to GI
-lacks anti-inflammatory properties
-safe dose 3g/day
-toxicity >7.5g
-liver failure 20-25g
adenosine Correct Answers inhibitory neurotransmitter through
which caffeine acts
-promotes sleep
-decreases release of NE and dopamine, decreases CNS
adverse effects of caffeine Correct Answers 200-500mg
irritability, insomnia, anxiety
adverse effects of orally administered corticosteroids Correct
Answers immunosuppression. cataracts, osteoporosis, and
hypertension
agonist Correct Answers activates receptor
-imitates response to natural neurotransmitter
alcohol uses Correct Answers safe drinking water in history
with calories
medicinal
, religious purposes
pleasure
allergic rhinitis Correct Answers inflammation of nose caused
by allergies
-mast cells and basophils react to allergens within the nose
-allergen binds to immunoglobulin (IgE)
-histamine is released which causes inflammation, mucosa
thickens and over produces mucus
allergies Correct Answers Inappropriate or excessive immune
responses to antigens
-mediated by histamine
allodynia Correct Answers Pain due to a stimulus that does not
normally provoke pain (gentle touch)
Amphetamines Correct Answers euphoria, dysphoria,
decreased fatigue, anorexia
anaphylaxis Correct Answers Life threatening allergic reaction
skin rash and swelling
throat swelling and tight chest
drop in BP
stomach pains, diarrhea, and vomiting
antagonist Correct Answers blocks activation of receptor
-prevents response to natural neurotransmitters
approved drugs for ADHD Correct Answers Ritalin and
Adderal
2 classes of drugs for flu Correct Answers tricylic amines
sialic acid analogs
2 mechanisms of GI irritation form NSAIDS Correct Answers -
direct irritation (aspirin)
-decreases mucous coating in stomach lining (mucous
production is regulated by prostaglandins)
3 factors that make up a drug Correct Answers 1. exogenous
substance
2. alters biochem or physiology
3. produces and effect
3 major drug classes for asthma Correct Answers
corticosteroids, anti-leukotrienes, and long-acting B2 agonists
3 major physiological function of histamine Correct Answers
immune response, neurotransmitter in CNS, regulation of GI
function
3 primary effects of NSAIDS Correct Answers reduce pain
(analgesic)
reduce fever (antipyretic)
reduce inflammation
3 signs of neuropathic pain Correct Answers hypersensitivity to
painful stimuli, spontaneous pain, and allodynia
,3 types of flu vaccines Correct Answers inactivated, live
attenuated, and recombinant (no actual virus, egg-free)
absorption of ethanol Correct Answers rapid, in the intestine,
slowed by food, max concentration after 30 mins
-crosses BBB and placenta
Acetaminophen Correct Answers -less irritating to GI
-lacks anti-inflammatory properties
-safe dose 3g/day
-toxicity >7.5g
-liver failure 20-25g
adenosine Correct Answers inhibitory neurotransmitter through
which caffeine acts
-promotes sleep
-decreases release of NE and dopamine, decreases CNS
adverse effects of caffeine Correct Answers 200-500mg
irritability, insomnia, anxiety
adverse effects of orally administered corticosteroids Correct
Answers immunosuppression. cataracts, osteoporosis, and
hypertension
agonist Correct Answers activates receptor
-imitates response to natural neurotransmitter
alcohol uses Correct Answers safe drinking water in history
with calories
medicinal
, religious purposes
pleasure
allergic rhinitis Correct Answers inflammation of nose caused
by allergies
-mast cells and basophils react to allergens within the nose
-allergen binds to immunoglobulin (IgE)
-histamine is released which causes inflammation, mucosa
thickens and over produces mucus
allergies Correct Answers Inappropriate or excessive immune
responses to antigens
-mediated by histamine
allodynia Correct Answers Pain due to a stimulus that does not
normally provoke pain (gentle touch)
Amphetamines Correct Answers euphoria, dysphoria,
decreased fatigue, anorexia
anaphylaxis Correct Answers Life threatening allergic reaction
skin rash and swelling
throat swelling and tight chest
drop in BP
stomach pains, diarrhea, and vomiting
antagonist Correct Answers blocks activation of receptor
-prevents response to natural neurotransmitters
approved drugs for ADHD Correct Answers Ritalin and
Adderal
