There are more a-1,4 bonds than a-1,6 bonds in glycogen. - ANSTrue
Glycogenin is an enzyme that uses glucose as a substrate. - ANSFalse
Following a meal, levels of muscle glycogen go up but liver glycogen levels stay the same. -
ANSFalse
The activity of glycogen synthase is increased when it becomes phosphorylated. - ANSFalse
The products of glycogen breakdown in muscle include glucose-1-P and free glucose. -
ANSTrue
Glucose-6-P is the main allosteric inhibitor of glycogen synthase. - ANSFalse
Which of the following statements about glycogen storage are INCORRECT?
- Glycogen is stored in muscles and the liver
- Glycogen reserves are less rapidly depleted than fat reserves during starvation
- Glycogen is a major source of stored energy in the brain
- Glycogen storage occurs in the form of dense granules in the cytoplasm of cells
- Glycogen nearly fills the nucleus of cells that specialize in glycogen storage - ANS- Glycogen
reserves are less rapidly depleted than fat reserves during starvation
- Glycogen is a major source of stored energy in the brain
- Glycogen nearly fills the nucleus of cells that specialize in glycogen storage
Which of the following features are common to both glycogen synthesis and glycogen
breakdown?
- Both require UDP-glucose
- Both occur on cytoplasmic glycogen granules
- Both involve glucose 1-phosphate
- Bothe use the same enzyme for branching and debranching
- Both are driven in part by the hydrolysis of pyrophosphate - ANS- Both occur on cytoplasmic
glycogen granules
- Both involve glucose 1-phosphate
Which of the following statements about the hormonal regulation of glycogen synthesis and
degradation are correct?
- Glucagon and epinephrine have opposing effects on glycogen metabolism
- Insulin increases the capacity of the liver to synthesize glycogen
- Glucagon stimulates the breakdown of glycogen, particularly in the liver
- The effects of epinephrine, glucagon, and insulin are mediated by cyclic AMP
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