The average person needs ___________ g of dietary protein per day - ANS70-100g
Neural effect - ANSPrepares the stomach for the protein on the way
GERD - ANSGastroesophageal reflux disease, otherwise known as heart burn
First step in the degradation of amino acids - ANSNitrogen removal
Excess amino groups are secreted from the body as _________ - ANSUrea
To get rid of the carbon skeletons, they are converted into _________ - ANSAlpha keto acids
Transamination - ANSAlpha amino acids + alpha ketoglutarate = alpha keto acids +
L-glutamate, catalyzed by aminotransferases, specific to each amino acid,in the cytosol
Oxidative deamination - ANSL-glutamate → alpha ketoglutarate + NH4, in the liver
Which two amino acids are not used in transamination? - ANSLysine and threonine
Pyrodoxal phosphate - ANSDerived from vitamin B6, it is needed as a coenzyme for
transamination
Urea cycle - general - ANSNH4 from oxidative deamination joins with co2 and aspartate, to form
urea
Aspartate aminotransferase - ANSUses the alpha ketoglutarate from oxidative deamination to
convert oxoloacetate into aspartate
How does the body process NH4 not produced in the liver or muscle? - ANSNH4 is usually
incorporated into glutamine by glutamine synthetase. Then, glutaminase in liver uses an H2O to
cleave the NH4 off of the glutamine
How does the body process NH4 produced in muscle? - ANSWhile small amounts get
converted to glutamine, most is transported as alanine. To form alanine, glutamine joins with
pyruvate, calalyzed by alanine aminotransferase. Once in liver, a group is transferred from
alanine to alpha ketoglutarate, reforming glutamate. The pyruvate released can be used for
gluconeogenesis, producing energy
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