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WGU D027 OBJECTIVE ASSESMENT EXAM VERSION A, B & C
ALL COMPLETE 500 QUESTIONS AND VERIFIED CORRECT
ANSWERS WITH EXPLANATIONS JUST RELEASED
WGU D027 OBJECTIVE ASSESMENT EXAM VERSION A
Which of the following is a self-limiting disease associated with Herpes type viruses and a
herald patch? - ANSWER-Pityriasis rosea -
Lichen planus, acne vulgaris, and erythema multiforme are conditions generally associated with
or caused by autoimmune dysregulation, bacteria, and varieties of foreign antigen
(medications, virus, etc.). Pityriasis rosea in particular is associated with and triggered by
Herpes viruses, manifesting itself as a herald patch.
What is a furuncle? - ANSWER-An infection of the hair follicle that extends to the surrounding
tissue -
Abscess, dermis, and fungal infections are generally more widespread or larger processes that
require broad or systemic treatment. A furuncle, though uncomfortable to painful, is a
generally localized infection that is self-resolving or that requires local, minor treatment.
What type of lesion may be malignant in the form of squamous cell carcinoma (SCC)? -
ANSWER-Actinic keratosis -
Actinic keratosis, which is caused by exposure to UV radiation, is a precursor lesion of SCC
What type of abnormal cell growth does carcinoma refer to? - ANSWER-Epithelial cells -
Carcinoma refers to dysplastic epithelial cells that have penetrated the entire thickness of the
epithelium into the basement membrane.
What is a characteristic of a malignant tumor? - ANSWER-Absence of normal tissue organization
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Healthy tissue is made up of non-cancerous cells that are well-differentiated, connected via a
well-organized stroma and that stay put. Malignant tumors lack those characteristics as well as
normal tissue organization.
Which lifestyle factor has not been linked to the development of cancer? - ANSWER-Extreme
exercise -
Tobacco use, obesity, and alcohol consumption are causal for numerous cancers, which can be
prevented. Exercise helps prevent colon cancer and likely helps prevent endometrial, breast,
and other cancers as well.
Which pediatric malignancy is linked to the family of origin? - ANSWER-Wilms tumor -
Wilms tumor is kidney cancer in childhood caused by inherited genes. The main causes of liver
cancer are hepatitis, fatty liver disease, and alcohol use. The main cause of cervical cancer is
HPV infection. Leukemia is caused by mutations to hematopoietic stem cells.
Which of the following drugs is classified as hormonal treatment for breast cancer? - ANSWER-
Tamoxifen -
Lapatinib is a tyrosine kinase inhibitor. Paclitaxil is an antimicrotubule agent. Rituximab is a
CD20-directed cytolytic monoclonal antibody. Tamoxifen is an anti-estrogen medication used in
the treatment of estrogen-linked breast cancer.
Where do the cancers treated with glucocorticoids stem from? - ANSWER-Lymphoid tissue -
Glucocorticoids, along with other medications, are used to treat cancers of the lymphoid tissue
(lymphocytic leukemias, Hodgkin disease, non-Hodgkin lymphomas, and multiple myeloma).
A 23-year-old woman comes in for prenatal counseling. While completing her family history,
she reports her brother has cystic fibrosis. She does not know if she is a carrier. She asks if her
children will be affected by the disease.
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What is an accurate way to determine the likelihood of this patient's children being affected? -
ANSWER-A genetic or a carrier test -
Cystic fibrosis is a hereditary disease that impacts the lungs and digestive system. It is the result
of the cystic fibrosis transmembrane conductance regulator gene mutation. The disease occurs
when an individual inherits the mutated gene from each parent. When only one mutated gene
is inherited, the individual is labeled a carrier.
A 31-year-old man comes into the office for an exam. He is 6' 5 " with a high-pitched voice, and
he has a moderate degree of mental impairment. It is discovered upon exam that his body hair
is sparse, his testes are small, and he has gynecomastia.
Which genetic disorder should this patient be tested for? - ANSWER-Klinefelter syndrome -
Klinefelter syndrome is a hereditary disease also known as 47,XXY or XXY that manifests as the
series of symptoms described. The symptoms are expressed as a result of the presence of two
or more X chromosomes in males. It is often not diagnosed until adulthood.
A six-month-old female infant with failure to thrive comes in to the office with her parents. It is
noticed upon exam that the patient has facial deformities and is jaundiced. A complete blood
count (CBC) is ordered, which reveals anemia. When that patient's blood is examined under a
microscope, the red blood cells appear small and abnormally shaped. A mutational analysis is
ordered, and alpha thalassemia is diagnosed.
What is the likelihood of incidence of these parent's future children having alpha thalassemia? -
ANSWER-25% -
Alpha thalassemia is a hereditary blood disorder characterized by reduction in hemaglobin
production. Each individual inherits two copies of the HBA1 gene and two copies of the HBA2
gene from each parent. If at least one copy of the four is missing, a variation of alpha
thalassemia can result. That means that future offspring have a one in four chance of the
disease.
Which chamber of the heart has the thinnest muscle in the heart? - ANSWER-Right atrium -
The ventricles possess cardiac muscles that are the thickest lined chambers of the heart
because their blood volume burden must be pumped to the lungs and the rest of the body,
which are areas of high resistance. The atria receive blood from either the rest of the body via
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the vena cava (right) or lungs (left). They must only pump the volume directly to the ventricles.
The coronary arteries encircle the chambers of the heart to supply the nutrients needed to
keep the tissue alive.
During diastole, which part of the heart is filling with blood? - ANSWER-Both ventricles -
Systole reflects the perfusing pressure of the cardiovascular system where the ventricles eject
blood from the heart. Once complete, a resting period—diastole—follows, where blood must
refill the ventricles directly from the collection that occurred in the atria.
Oxygenated blood flows through which vessel? - ANSWER-Pulmonary vein -
The superior vena cava carries all the deoxygenated blood from peripheral circulation back to
the heart where it enters the right atrium to be pumped into the right ventricle. The right
ventricle pumps to the lungs for oxygenation via the pulmonary artery. After pulmonary
circulation, the oxygenated blood is carried back to the heart via the pulmonary vein.
Which complex (wave) represents the sum of all ventricular muscle cell depolarizations? -
ANSWER-QRS -
The QRS wave of an electrocardiogram (ECG or EKG) represents the largest spike in electrical
activity of the heart, as ventricular muscle cells perform the highest burden of work to pump
blood volume out of the heart in that instance.
What effect does atherosclerosis have on the development of an aneurysm? - ANSWER-Erodes
the vessel wall -
Atherosclerosis, also known as the process of "hardening of the arteries" and secondary to
plaque formation, weakens the flexibility of a blood vessel wall. Without vascular compliance,
the vessel wall becomes more rigid and susceptible to rupture (i.e., an aneurysm).
What is the effect of oxidized low-density lipoproteins (LDLs) in atherosclerosis? - ANSWER-LDLs
cause smooth muscle proliferation -
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