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Claytons Basic Pharmacology for Nurses 19th Edition By Bruce Clayton, Michelle Willihnganz, Samuel Gurevitz 9780323796309 / Chapter 1-48 / All Chapters with Answers and Rationals$17.99
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Claytons Basic Pharmacology for Nurses 19th Edition By Bruce Clayton, Michelle Willihnganz, Samuel Gurevitz 9780323796309 / Chapter 1-48 / All Chapters with Answers and Rationals
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Claytons Basic Pharmacology for Nurses 19th Edition By Bruce Clayton, Michelle Willihnganz, Samuel Gurevitz 9780323796309 / Chapter 1-48 / All Chapters with Answers and Rationals
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Test Bank for Clayton's Basic Pharmacology for Nurses 18th Edition By Michelle Willihnganz; Samuel L. Gurevitz; Bruce D. Clayton Chapter 1-48 Complete Guide A+
TESTBANK FOR CLAYTON’S BASIC PHARMACOLOGY FOR NURSES 20TH EDITION BY MICHELLE J. WILLIHNGANZ, SAMUEL L. GUREVITZ, BRUCE CLAYTON
Claytons Basic Pharmacology for Nurses 19th Edition By Bruce Clayton, Michelle Willihnganz, Samuel Gurevitz 9780323796309 / Chapter 1-48 / All Chapters with Answers and Rationals
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Test Bank For Claytons Basic Pharmacology for Nurses 19th
Edition By Bruce Clayton, Michelle Willihnganz, Samuel
Gurevitz 9780323796309 / Chapter 1-48 / All Chapters with
Answers and Rationals
drugs do not create new responses but rather - ANSWER: alter existing physiologic activity in several
different ways
specific sites which the drug usually forms chemical bonds with - ANSWER: receptors
a drug only forms a bond with a receptor if: - ANSWER: - the drug and the receptor have similar
shapes
- the drug has a chemical affinity for the receptor
the study of the interactions between drugs and their receptors and the series of events that result in
a pharmacologic response - ANSWER: pharmacodynamics
T/F: the better the fit between the receptor and the drug molecule the better the response of the
drug - ANSWER: T
drugs that interact with a receptor to stimulate a response are known as - ANSWER: agonists
drugs that attach to a receptor but do not stimulate a response - ANSWER: antagonists
drugs that interact with a receptor to stimulate a response but inhibit other responses - ANSWER:
partial agonists
3 routes of drug administration: - ANSWER: - enteral
- parenteral
- percutaneous
when using the _______________ route, the drug is administered directly into the GI tract by oral,
rectal, or nasogastric route - ANSWER: enteral
when using the _________________ route, the drug bypasses the GI tract with the use of
subcutaneous, intramuscular, or intravenous injection - ANSWER: parenteral
when using the ___________________ route, the drug is absorbed through the skin and mucous
membranes - ANSWER: percutaneous
after administration, all drugs go through 5 stages: - ANSWER: - liberation
- absorption
- distribution
- metabolism
- excretion
the study of what the body does to the drug - ANSWER: pharmacokinetics
release of a drug from the dosage form to be dissolved in body fluids for absorption - ANSWER:
liberation
liberation of a drug within the body can be manipulated by: - ANSWER: - pharmaceutical dosage form
used (e.g. solution, suspension, capsule, tablet)
, - administering the drug with or without food and water in the patient's stomach
the process whereby a drug is transferred from its site of entry into the body to the circulating fluids
of the body for distribution around the body - ANSWER: absorption
the rate at which a drug is absorbed depends on: - ANSWER: - route of administration
- blood flow through the tissue where the drug is administered
- solubility of the drug
the rate of absorption when a drug is administered by a parenteral route depends on the - ANSWER:
rate of blood flow through the tissues
absorption of a drug is slowest when administered this way - ANSWER: subcutaneous injection
T/F: after a drug enters a patient's bloodstream, it is still retrievable - ANSWER: F
the absorption of topical drugs that have been applied to the skin can be influenced by: - ANSWER: -
drug concentration
- length of contact time
- size of the affected area
- thickness of the skin surface
- hydration of tissue
- degree of skin disruption
when drugs are inhaled, their absorption can be influenced by: - ANSWER: - depth of the patient's
respiration
- fineness of the droplet particles
- available surface area of the patient's mucous membranes
- contact time
- hydration state
- blood supply to area
- concentration of the drug itself
refers to the ways in which a drug is transported throughout the body by the circulating body fluids to
the sites of action or to the receptors that the drug affects - ANSWER: distribution
organs with the most extensive ______________ supply receive the distributed drug most rapidly -
ANSWER: blood
two factors influencing drug distribution: - ANSWER: - protein binding
- lipid/fat solubility
only the _______________ portion of a drug is able to diffuse into tissues, interact with receptors,
and produce physiologic effects - ANSWER: unbound
more lipid-soluble drugs have a high affinity for ________________ tissue, which serves as a
repository site for these agents - ANSWER: adipose
T/F: the same proportions of bound and free drug are maintained in the blood at all times - ANSWER:
T
the process whereby the body inactivates drugs - ANSWER: metabolism
the enzyme systems of the __________ are the primary sites for the metabolism of drugs - ANSWER:
liver
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