Chapter 46- Zidovudine Actual Questions And Answers Guaranteed Pass A+ Score.
3 views 0 purchase
Course
AZT
Institution
AZT
Pharmacotherapeutics - correct answer Active against the Epstein-Barr virus and hepatitis B virus (HBV) and used for HIV and AIDS. CD4 count of 200-350
Pharmacokinetics - correct answer Orally or parenter...
Chapter 46- Zidovudine
Pharmacotherapeutics - correct answer Active against the Epstein-Barr virus
and hepatitis B virus (HBV) and used for HIV and AIDS. CD4 count of 200-350
Pharmacokinetics - correct answer Orally or parenterally
Crosses the blood-brain barrier and placenta.
Needs to be activated
Pharmacodynamics - correct answer Inhibits the synthesis of DNA by inhibiting
reverse transcriptase (the viral enzyme that copies viral RNA into DNA). The reverse transcriptase does
not recognize the difference btwn HIV and AZT so DNA chain is prematurely terminated. This occurs in
the nucleus.
C/P - correct answer Hypersensitivity, breast-feeding, and existing lactic
acidosis. Precautions with pre-existing hepatic dysfunction, obesity.
Adverse Effects - correct answer GI symptoms include nausea and vomiting,
diarrhea, abdominal pain, dyspepsia, and anorexia. CNS effects have been reported, including headache,
seizures, somnolence, paresthesias, agitation, restlessness and insomnia.
Hematologic toxicities, including granulocytopenia and sever anemia.
Severe: Myopathy
Lactic acidosis
Drug Interactions - correct answer ganciclovir used to treat retinitis, tylenol,
interferon, rifampin.
Health Status - correct answer Assess the patient for hypersensitivity and for
pregnancy, pre-existing hepatic or renal dysfunction. Before therapy complete a physical exam. Lab tests
include CD4 count, liver and renal function etc.
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller RealGrades. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $12.99. You're not tied to anything after your purchase.
