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Nuclear Medicine, PET, SPECT/CT Imaging Questions and Answers

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Nuclear Medicine, PET, SPECT/CT Imaging Questions and Answers What does nuclear medicine evaluate? How organs are functioning (physiology) to help detect pathology at the molecular level - differs from other modalities because it doesn't show changes in anatomy Where is the preparation of ...

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  • August 21, 2024
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  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NucMed
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Nuclear Medicine, PET, SPECT/CT
Imaging Questions and Answers
What does nuclear medicine evaluate? - answer How organs are functioning
(physiology) to help detect pathology at the molecular level - differs from other
modalities because it doesn't show changes in anatomy

Where is the preparation of pharmaceuticals done? - answer In the radiopharmacy

What are the 2 parts of radiopharmaceuticals? - answer The drug portion (goes to
the source), and the radioactive isotope (so we can see it)

How can radiopharmaceuticals be administered? Is there any pain or side effects
associated with the drugs? - answer Injected into a vein in the arm, orally, or inhaled
depending on the study
- no pain or side effects

What is the most common nuclide? What E does it have? - answer technetium 99-m
(Tc-99m), 140 keV

What is the half life of technetium 99-m? How long does it take to be completely
voided? - answer 6 hour half life, 24 hours to be completely voided

How are images obtained? - answer - gamma radiation is emitted from within the
patient (as opposed to through the pt)
- emission of gamma photon represents the location of the radionuclide w/in the
structure
- information emitted is captured by a detector
- function determined by intensity of gamma radiation emitted

What are contraindications for a nuclear medicine study? - answer - no barium for 48
hours
- no previous NM tests

What is the appropriate preparation for a NM test? - answer Fasting and stopping
medications

Why are patients allowed to stay clothed? - answer Because you're using higher
energy photons so clothing doesn't leave artifacts

What is the range of exam lengths for NM testing? - answer 30 min to several days

, What are some test-specific history questions? - answer Broken bones, bone
disease, renal disease, surgery to the bones, cancer, etc.

What do hot spots demonstrate? - answer Areas of increased uptake

What do cold spots demonstrate? - answer Areas of decreased uptake

What does CNS NM testing determine and measure? What radionuclide is used? What
is the diagnostic correlation? - answer Brain viability and measures the regional
cerebral blood flow to assess if there is sufficient activity to sustain life
- 99m Tc-Bicisate (Neurolite)
- EEG

What does pulmonary system NM test used to diagnose? What are you looking for?
What radionuclide(s) are used? What is the diagnostic correlation? - answer Used to
diagnose pulmonary embolism by looking at both the ventilation/air flow and
perfusion/b+ flow of the lungs
- looking for a "mismatched" defect
- 99 Tc-DTPA and 99m Tc-MAA
- CXR, CT, US (to assess for CVT), MRA
(Normal pulmonary scan)

What are the 2 phases of pulmonary system NM testing? - answer Ventilation -
assess air flow to the lungs by breathing in a radioactive aerosol
Perfusion - assess b+ flow to the lungs by injecting the radioactive tracer IV
(Scan w/ pulmonary embolism)

What is myocardial perfusion imaging differentiating? What is the diagnostic
correlation? - answer Differentiates between ischemia and infarction - aids in the
diagnosis and mgmt of CAD regionally and globally
- diagnostic correlation: coronary angiography, exercise stress test, echocardiogram, b+
test (cardiac enzymes)
- SPECT/CT

What are examples of therapeutic uses of myocardial perfusion imaging? - answer
CABG, angioplasty/stent, pacemaker, valve replacement

Stress/Rest Tests - answer

What different formats can images be obtained in? - answer Planar, dynamic, and
3D

What radiopharmaceuticals does SPECT imaging use? - answer The same as NM

What does SPECT stand for? - answer Single photon emission computed
tomography

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