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MCB4271 Final Exam Questions And Correct Answers
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MCB4271 Final Exam Questions AndCorrect Answers
Antibiotic resistance occurs naturally, but the _____ of drugs in humans and animals is
accelerating the process. - Answer underuse, use, and overuse
On average, how long does it take for the development of clinical resistance to an
antibiotic? - Answer 8 years
Factors contributing to AMR in healthcare include (choose the best answer) - Answer
lack of antibiotics, poor sanitation, inadequate infection controls
The use of antibiotics in farm animals has been ______ in 1951. - Answer approced
What are the reasons that make it difficult to eliminate antibiotics from their use in farm
animals? - Answer loss of profit to animal farming companies, loss of profit to
pharmaceutical companies, easy access to antibiotics
Major host reservoirs that are exposed to antibiotic selective pressure include the
following: - Answer Food animals, pets, and humans
What is the problem associated with the Citrus Greening Disease? - Answer Massive
application of clinically-important antibiotics on citrus crops
Johnny developed a MRSA infections when he got injured during his baseball practice.
Johnny got a _____ acquired infection. - Answer community
According to the WHO, antimicrobial resistance is one of the biggest threats to global
health and food security today. - Answer True
Check all the reasons why antibiotics are used in food animals: - Answer Growth
promotion (although banned in 2017), infection control
All strains of mold produce penicillin. True/False - Answer False
The structure of beta-lactam antibiotics resemble: - Answer a house
beta-lactam antibiotics are characterized by: - Answer a 4-member ring containing a
nitrogen
penicillinases are - Answer enzymes that deactivate penicillin
The structure below is D-ala-Dala dipeptide. What is its function? - Answer
peptidoglycan terminus
clavams are very potent antibiotics - Answer false
What is this antibiotic (structure covering D-Ala-D-Ala - Answer vancomycin
, What is the function of the penicillin binding protein? - Answer to crosslink
peptidoglycan
What is this antibiotic? (5-membered ring containing O and NH. NH2 and double bonded
O form bonds with C in the ring) - Answer Cycloserine
Carbapenems are effective against 98% of bacterial strains isolated from hospitals.
There is a special caution of using this antibiotic to avoid the development of resistance.
- Answer True
Conversion of dihydrofolate back to tetrahydrofolate is essential to keep a constant
supply of which nucleotide? - Answer dTTP
What is the functino of dihydrofolate reductase (DHFR)? - Answer converts
dihydrofolate to tetrahydrofolate
Trimethroprim binds to human DHFR - Answer False
Inhibiting DNA synthesis arrests the cell cycle but does not kill cells. Hence,
trimethroprim is classified as a bacteriostatic antibiotic. - Answer True
Sulfanilamide is an antibiotic. - Answer False
Structural differences between eukaryotic and prokaryotic machinery involved in the
Central Dogma of Molecular Biology (replication, transcription, translation) allow for the
development of antibiotics that specifically target microbial cells. - Answer True
What is this antibiotic? i cant describe this picture lol - Answer Fluorquinolone
Quinolone antibiotics target DNA gyrase and topoisomerase IV. These type II
topoisomerases are also found within the human proteome. - Answer False
Which of the following statements is true about rifampin? - Answer It inhibits bacterial
RNA polymerase.
What is the function of sulfanilamide? - Answer inhibits dihydropteroate synthase
The antibiotic structure show below is (4 six-membered rings) - Answer a tetracycline
Tetracyclines bind to the 50S ribosomal subunit. - Answer False
Chloramphenicol binds to 50S ribosomal subunit and inhibits peptidyl transferase -
Answer True
What is the function of the hydrophobic fatty acid chain in lipopeptides? - Answer Allows
the antibiotic to penetrate cell membrane
The majority of antibiotic classes were developed during the Golden Age of antibiotics.
Since then, very few new classes were introduced into clinical use. - Answer True
Hemoperfusion devices - Answer Filtering blood from bacteria
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