drug - Chemical that affects physiologic process of a living organism
Nursing Implications - The concepts that a nurse must include when they are safely administering
medication
Identify the various routes of medication administration - Sublingual (buccal), oral, transdermal (topical
creams/ lotions), instillation (eye drops/sprays), inhalation, nasogastric and gastrostomy tubes,
suppositories, parenteral
6 rights of administration - 1. Right patient
2. Right drug
3. Right dose
4. Right route
5. Right time and frequency
6. Right documentation
List the components of a drug label - Chemical Name: structure of the drug
Generic name: the official drug name
Brand/ trade name: the easier proprietary name
Active and inactive ingredients
Warning/ possible side effects
Directions on use as well as what the drug is used for/ what it helps treat
normal vital signs (BP) - 120/80
, Pharmacokinetics - what the body does to the drug
pharmacokinetic phases - -absorption (drug movement from GI tract into bloodstream)
-distribution (protein binding, free drugs, BBB)
-metabolism (1/2 life, loading dose; liver)
-excretion (elimination, kidneys, creatinine clearance, BUN, GFR
factors that affect drug excretion - -drugs that affect renal excretion/decrease CO
-diuretic use
-drugs that use same excretion method
-change of urine pH
-pt. with decreased renal or hepatic function
1/2 life (T 1/2) - Time it takes to get rid of half of the drug; gives us good time to administer rest of the
dose and when we can expect to see side effects
Loading dose - use of a higher dose than what is usually used for treatment to allow the drug to reach
the critical concentration sooner
photosensitivity - - sensitivity to light
- ranges from the ability to orient to the sun to the ability to see
factors affecting absorption - Blood circulation
Pain, stress
Food texture, fat content, temperature
pH
Route of administration
factors affecting bioavailability - Drug form
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