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ASCP Coagulation & Hemostasis Exam Questions and Complete Solutions Graded A+
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ASCP Coagulation & Hemostasis Exam Questions and Complete Solutions Graded A+
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ASCP Coagulation &Hemostasis Exam
Questions and Complete
Solutions Graded A+
Denning [Date] [Course title]
, Primary hemostasis - Answer: Vasoconstriction
platelet adhesion
platelet aggregation to form hemostatic plug at injury site
Secondary hemostasis - Answer: interaction of coag factors to produce fibrin
fibrin stabilization by factor XIII
Fibrinolysis - Answer: release of plasminogen activator
conversion of plasminogen to plasmin
conversion of fibrin to fibrin degradation products
Prothrombin time (PT) - Answer: Used to detect the deficiencies in the EXTRINSIC & COMMON
pathways. Monitor COUMADIN (warfarin) therapy. Use along w/ INR
(II,VII,X,V,I)
Can be stored for up to 4 hours at 4C
Activated Partial Thromboplastin time (APTT) - Answer: Used to detect deficiencies in the INTRINSIC &
COMMON pathways. Monitor using HEPARIN
(V,X,VIII,IX,XI,XII,PK,I,II)
D-Dimer - Answer: Used as a marker for DIC
Factor VII deficiency - Answer: Prolonged PT ; normal APTT
Factors PK,XII,XI,IX,VIII deficiencies - Answer: normal PT; prolonged APTT
Factor X,V,II,I deficiency - Answer: prolonged PT; prolonged APTT
Removal of the spleen - Answer: This might be the last resort in a patient ITP...
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