MGCCC Nursing Pharmacology Exam
Study Guide
Sulfamethoxazole-Trimethoprim/TMP-SMZ (Actions) - Answer Inhibit bacterial synthesis
of folic acid
Bacteriostatic
Fights gram - bacteria
Proteus, Klebsiella, E. coli, Chlamydia
Sulfamethoxazole-Trimethoprim/TMP-SMZ (uses) - Answer Otitis media, respiratory
infections
UTIs, prostatitis, gonorrhea
Sulfamethoxazole-Trimethoprim/TMP-SMZ (Routes) - Answer Oral, IV, topical,
ophthalmic
Sulfamethoxazole-Trimethoprim/TMP-SMZ (Contraindications) - Answer Br feeding
infants <2mo. Hypersensitivity, term pregnancy, megaloblastic anemia, chancroid,
traveler's diarrhea
Sulfamethoxazole-Trimethoprim/TMP-SMZ (Side Effects) - Answer Mild to moderate
rash, photosensitivity
GI distress, stomatitis, crystalluria
Fatigue, depression, headache, dizziness
Sulfamethoxazole-Trimethoprim/TMP-SMZ (Adverse Reactions) - Answer Blood
dyscrasias
Stevens-Johnson syndrome
Renal failure
Sulfamethoxazole-Trimethoprim/TMP-SMZ (Nursing Interventions) - Answer Administer
with full glass of water 1 hour before meals or 2 hours after meals.
Increase fluid intake.
Monitor for sore throat, bruising, bleeding.
Monitor CBC.
Check for superinfection.
, Advise client not to take with antacids.
Tell client to avoid direct sunlight.
Use alternate forms of OCP
Avoid OTC (asa, vit.C)
Sulfamethoxazole-Trimethoprim/TMP-SMZ (Drug Interaction) - Answer Warfarin
Increases anticoagulation
Oral hypoglycemic
Increases hypoglycemia
Sulfamethoxazole-Trimethoprim/TMP-SMZ (class) - Answer Sulfonamides
Nitrofurantoin (Macrodantin) (class) - Answer Anti-infective
Nitrofurantoin (Macrodantin) (Actions/uses) - Answer Inhibits bacterial UTIs caused by E
coli, Klebsiella, Pseudomonas, Proteus vulgaris & morganii, Staph aureus, &
epidermidis, enterococcus, salmonella, shigella
Nitrofurantoin (Macrodantin) (Contraindications) - Answer Infant <1 mo,
hypersensitivity, anuria, severe renal disease CCr <60 mL/min, term pregnancy, labor,
delivery
Nitrofurantoin (Macrodantin) (side effects) - Answer Dizziness, h/a, drowsiness,
peripheral neuropathy, chills, confusion, vertigo, CP, n/v/d, abd pain, loss of appetite,
pruritus, rash, angioedema, alopecia, tooth staining, arthralgia, myalgia, numbness,
cough, dyspnea, pneumonitis, pulmonary fibrosis or infiltrate, SLE-like syndrome
Nitrofurantoin (Macrodantin) (Adverse reactions) - Answer Bundle-branch block,
cholestatic jaundice, pseudomembranous coilitis, hepatitis, pancreatitis, anemia,
agranulocytosis, hemolytic anemia, leukopenia, thrombocytopenia, exfoliative
dermatitis, Stevens-Johnson syndrome, superinfection
Nitrofurantoin (Macrodantin) (Nursing Implications) - Answer Report continued
symptoms
Take with food or milk, avoid ETOH
Protect from freezing, shake well
May cause drowsiness, seek aid with walking & other activities (driving or operating
machinery)
Monitor blood glucose in diabetes
Instruct urine may turn urine rust-yellow to brown