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ATI Pharmacology CH. 1 Exam Questions & Answers Scored A+
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Sublingual and buccal absorption - CORRECT ANSWER-Quick absorption systemically through highly vascular mucous membranes. Rectal and vagina absorption - CORRECT ANSWER-Easy absorption with both local and systemic effects Absorption with Inhalation via mouth, nose. - CORRECT ANSWER-Rapid absor...

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  • August 22, 2024
  • 6
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • ati pharmacology ch 1 exam questions answers sc
  • ati pharmacology ch 1 exam questions stuvia
  • sublingual and buccal absorption correct answer

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ATI Pharmacology CH. 1 Exam
Questions & Answers Scored A+

Sublingual and buccal absorption - CORRECT ANSWER-Quick absorption systemically
through highly vascular mucous membranes.



Rectal and vagina absorption - CORRECT ANSWER-Easy absorption with both local
and systemic effects



Absorption with Inhalation via mouth, nose. - CORRECT ANSWER-Rapid absorption
through alveolar capillary networks



Intradermal, topical absorption - CORRECT ANSWER-Slow, gradual absorption.



Effects primarily, but systemic as well, especially with lipid-soluble medications passing
through subcutaneous fatty tissue.



Subcutaneous, Intramuscular absorption - CORRECT ANSWER-Solubility of the
medication in water:

-Highly soluble medications have rapid absorption (10 to 30 min)

-Poorly soluble medications have slow absorption.



Blood perfusion at the site of injection:

-Sites with high blood perfusion have rapid absorption

-Sites with low blood perfusion have slow absorption.



Intravenous absorption - CORRECT ANSWER-Immediate: enters directly into the blood

Complete: Reaches the blood in its entirety

, What are barriers to intravenous absorption? - CORRECT ANSWER-There are no
barriers.



What are the barriers to subcutaneous and intramuscular absorption? - CORRECT
ANSWER-Capillary walls have large spaces between the cells. Therefore, there is no
significant barrier.



What are barriers to intradermal, and topical absorption? - CORRECT ANSWER-Close
proximity of epidermal cells.



What are barriers to inhalation? - CORRECT ANSWER-Inspiratory effect



What are the factors influencing distribution? - CORRECT ANSWER-Circulation,
permeability of the cell membrane, plasma protein binding,



Where does excretion take place? - CORRECT ANSWER-The kidneys. Elimination also
takes place through the liver, lungs, intestines, and exocrine glands (such as breastmilk)



Kidney dysfunction can lead to what? What is important to monitor? - CORRECT
ANSWER-It can lead to an increase in the duration and intensity of a medications
response, so it is important to monitor BUM and creatinine levels.



Therapeutic index (TI) - CORRECT ANSWER-High level: have a wide safety margin so
there is no need for routine serum medication-level monitoring.



Low: Require close monitoring of the serum medication levels.



Half-life - CORRECT ANSWER-Liver and Kidney function affect Half-life.



It usually takes 4 half-lives to achieve a steady state of serum concentration (medication
intake=Medication metabolism and excretion.)



MEC - CORRECT ANSWER-Minimum effective concentration

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