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NAPLEX Test Bank Final Questions and answers | Latest 2024/25 RATED A+
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NAPLEX Test Bank Final Questions and answers | Latest 2024/25 RATED A+
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NAPLEX Test Bank Final Questions andanswers | Latest 2024/25 RATED A+
Binds to cell membrane causing depolarization, DNA/RNA/protein synthesis inhibition -
II II II II II II II II II II
Daptomycin
II
Ceftaroline adverse effects (3) - Positive direct Coombs' test
II II II II II II II II II II
Thrombocytopenia post-marketing II
caution renal impairment II II
Inhibits bacterial protein synthesis by binding to 50S
II II II II II II II II
FDA approved for complicated skin and skin structure infections -
II II II II II II II II II II
Quinupristin/Dalfopristin 7.5 mg/kg q8hr
II II II II
Quinupristin/Dalfopristin adverse effects (3) - hyperbilirubinemia
II II II II II II II
pain/INF at infusion sites II II II
myalgia
II Covers aerobic/anaerobic bacilli - 2G Ceph (Cefuroxime)
II II II II II II II
Concentration-dependent bacteriocidal that covers GM , GN , mycobacterium, and
II II II II II II II II II II
atypicals - Fluoroquinolones (Ciprofloxacin)
II II II II II
II Prothrombin Complex Conc (PCC) max dose - 20 mL/min II II II II II II II II II
II 6 mg/kg IV daily - Daptomycin dose
II II II II II II II
II Docetaxil side effect - neutropenia II II II II II
Trad AG (Gent/Tobra) dose - 1-2.5 mg/kg IV q8hr
II II II II II II II II II II
Peak 5-10, Trough <2
II II II
II LABA Olodaterol MDI daily - Striverdi Respimat
II II II II II II II
CYP-450 Inhibitors BIG FACES.COM - Bupropion, Itraconazole, Gemfibrazole
II II II II II II II II II
Fluoxetine, Amiodarone, Cipro II II
Erythromycin, SMX-TMP, Clopidogrel II II
Omeprazole, Metronidazole II
Lefluonamide (Arava) DMARD reversal agent - Cholestyramine 8 mg TID for 11 days
II II II II II II II II II II II II II II
(OUTCH)
II
II What antihypertensive class should avoid GFJ? - All CCB are CYP3A4 substrates
II II II II II II II II II II II II
,Room temp storage of insulin (3) - Tresiba - 8 weeks
II II II II II II II II II II II II
Levemir - 6 weeks II II II
Humalog/Novolog, Lantus - 3 weeks II II II II
What drug should be stopped before using ketoconazole or itraconazole for
II II II II II II II II II II II
onychomycosis - PPI (Rabeprazole)
II II II II II
II Mycobacterium avium - Clarithromycin/Azithromycin + Ethambutol II II II II II II
II Trilafon - Perphenazine II II II
II Antipsychotic not for 3A4 inducers and dehydrate - Cariprazine (Vraylar) II II II II II II II II II II
Daptomycin adverse effects (2) - Increased creatine phosphokinase - monitor weekly
II II II II II II II II II II II II
insomnia
II 2C9 (3) inhibitors - Bactrim, cranberry juice, metronidazole
II II II II II II II II
II Good for Gram (+) Strep - Narrow spectrum PCNs (G and V)
II II II II II II II II II II II II
PCN for Gram (+) AND Gram (-) - 1. Aminopenicillins (Amoxicillin, Ampicillin)
II II II II II II II II II II II II II
2. ANtipseudomonal (Pipercillin, Ticarcillin)
II II II
II Schizophrenia algorithm - SGA -> FGA -> Clozapine II II II II II II II II
II Protein synthesis 50S translocation inhibitor - Clindamycin
II II II II II II II
II Used in uncomplicated UTI and covers GP, GN (VRE) - Nitrofurantoin
II II II II II II II II II II II
II May cause (+) Coombs' test, thrombo, renal - Ceftaroline
II II II II II II II II II
Renal drug that is not 3A4 metabolized but levels are increased by 3A4 inhibitors -
II II II II II II II II II II II II II II II II
DIgoxin - CYP AND PGP
II II II II II
CYP3A4 Inducers (7) - 1. Carbamazepine, Dexamethasone, Isoniazid
II II II II II II II II II
2. Phenobarbital, Phenytoin, Prednisone
II II II
3. RIfampin
II
II Risk with TCA (Imipramine) and Sertraline - Serotonin Syndrome
II II II II II II II II II
II Trastuzumab dose in breast CA - 4 mg/kg II II II II II II II II
CYP 3A4 inhibitors (8) - 1. Cimetidine, Clarithromycin, Azoles
II II II II II II II II II II
2. Diltiazem, Verapamil, select SSRIs
II II II II
3. Grapefruit juice, omeprazole
II II II
, Daunorubicin (Cerbidine) anticancer dose - 30-60 mg/m2 for 3-5 days (Lifetime dose
II II II II II II II II II II II II II
550)
II
II Methotrexate (Amethopterin) dose used in cancer - 1 g/m2 II II II II II II II II II
1st line agent in chronic asthma that can systemically cause insomnia, fluid retention,
II II II II II II II II II II II II II
hyperglycemia and inhaler can cause cough, thrush, and hoarseness - ICS (Fluticasone)
II II II II II II II II II II II II II
Antihypertensives to use in AFib - Metoprolol TARTRATE (BID), Non-DHP CCB
II II II II II II II II II II II II
(Verapamil)
II
G6PD deficiency nemia - Nice Police Dogs Probably Smell - their Method in Criminal
II II II II II II II II II II II II II II
Cases (8) - 1. Nitrofurantoin, Primaquine, Dapsone
II II II II II II II II
2. Probenacid, Sulfonamide
II II
3. Methyline Blue, Chloroquine, Rasburicase
II II II II
Drugs that raise blood sugar - SSSweet Food and Drugs Can Buildup iN People (9) - 1.
II II II II II II II II II II II II II II II II II II
Statin, Steroid, SGA
II II II
2. FQ, Diuretic, Cyclosporine
II II II
3. BB/B-agonists, Niacin, PIs
II II II
Acid-Base Disorders - pH 7.35-7.45 (acidic/basic)
II II II II II II II
pCO2 35-45 SAME (metabolic), DIFF (respiratory)
II II II II II
Calcium conversions - Carbonate 40%
II II II II II II
Citrate 21% II
Acetate for phos binding (NOT Ca) 25%
II II II II II II
II specific gravity - g/mL II II II II
PCN given on empty stomach and one with food - Penicillin VK (Veetids) - empty
II II II II II II II II II II II II II II II II
stomach
II
Amoxicillin - with food II II II
II Amoxicillin DOC for (3) - Ear infection, H. pylori, endocarditis
II II II II II II II II II II
Extended spectrum PCNs for SSTI, endocarditis, or bone/joint infection (3) - Nafcillin
II II II II II II II II II II II II II
(Nafcillin, Nallpen)
II II
Oxacillin (Bactocillin) II
Dicloxacillin (Dynapen) II
Cephalosporin for Streptococcal/Pseudomonas (5) - Cefdinir, CefTAZ, CefTRIaxone
II II II II II II II II II
Cefotaxime, Cefixime II
II Cephalosporin side effects (2) - Renal toxicity, C. diff colitis II II II II II II II II II II
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