Biochemistry Exam 1*******
Hydrocarbons - ANS Most biomolecules can be considered to be derivative of
protein synthesis - ANS The most prominent function of RNA is
anabolic - ANS Energy requiring metabolic pathways that yield complex molecules from simpler
precursors ar
nuclear envelope - ANS In eukaryotes, the nucleus is enclosed by a double membrane called
the
Nucleoid - ANS In place of a nucleus a prokaryotic cell has a
rapid cell division. - ANS Notable features of eukaryotes include all of the following except ____
they have: Larger size, a complex internal structure, an endomembrane system, organelles
one of the strongest electrostatic bonds between hydrogen and oxygen or nitrogen - ANS A
hydrogen bond is best defined as
NH3+ - ANS Which of the following groups of molecules can participate in a hydrogen bond as a
hydrogen bond donor?
(CH3NH2, HOCH2CH2OH) - ANS Which of the following compounds is capable of hydrogen
bonding with like molecules ______
hydrogen bonds - ANS Which of the following factors is responsible for the fact that water is a
liquid at room temperature?
High heat of fusion, vaporization and heat capacity - ANS Which of the following properties of
water promotes the relatively constant climate of earth?
HNO3 - ANS Which of the following molecules are weak acids?
Delta E of reaction, the ratio of products to reactants of a reaction, entropy and enthalpy of a
reaction. - ANS Determination of delta G:
If the value was too negative the overall metabolism of ATP would be too difficult. - ANS Why
does the hydrolysis of ATP to ADP have a middle of the road, negative delta G value? _______
,H2(+0.0424V) - ANS Which of the following is the strongest reducing agent? ( The standard
reduction potential of each species is provided in the parenthesis) _____
reducing agent. - ANS In any redox rxn, an electron donor is the
NADH and FADH2 - ANS in biological systems most energy generating redox rxn involve
hydride ion transfer or hydrogen atom transfer using which of the following?
L - ANS Which of the following amino acids contain a hydrophobic side chain?____
omega - ANS There are 3 labeled bonds for each amino acid of a protein. Which of the following
bonds is non-rotatable.
The sequence of amino acids in the protein - ANS The three dimensional structure of a protein
is determined primarily by: _____
Phosphorylation, acetylation, proteolytic cleavage, glycosylation - ANS Which of the following is
an example of posttranslational modification of proteins? ____,___,___,___
ionic interactions - ANS Salt bridges in proteins are an example of ___
decreasing the activation energy - ANS Enzymes are biological catalysts that enhance the rate
of a reaction by _____
the sequence of amino acids in the protein. - ANS The 3D structure of a protein is determined
primarily by _____
Nucleic Acids, proteins, Carbs - ANS Which of the following macromolecule families commonly
form long. Linear polymers of undefined length from their monomeric precursors? ___,___,____
Condensation Reaction - ANS The rxn that catalyzes the polymerization of carbs and proteins
are both what kind of reaction?____
Participates in structural support of the cell & Controls the flow of substances in and out of the
cell - ANS The plasma membrane does which of the following? ____
flagella - ANS Prokaryotes and Eukaryotes differ in all of the following except for having a ___
There contain opposite charges that result from a severe disparity between atoms. - ANS Which
of the following is true about ionic bonds? ____
Disulfide bond - ANS Which of the following is a type of covalent bond? ____
,One of the strongest electrostatic bonds between hydrogen oxygen or nitrogen - ANS A
hydrogen bond is best defined as: ___
hydrophobic effect. - ANS The tendency of nonpolar molecules to aggregate in a water medium
is called ____
pH, pKa - ANS Which are True?
If the_____ of the solution is known as is the _____for the acid, the ratio of conjugate base to
acid can be determined. At pH= pKa for an acid, there is an equal amount of conjugate base to
acid in solution. At pH greater than pKa for an acid, the acid will be mostly
deprotonated(ionized), At pH less than 1 unit from a molecule's pKa, the acid will mostly be
protonated (deionized)
conjugate base, acid - ANS Which are True?
If the pH of the solution is known as is the pKa for the acid, the ratio of __ to ____ can be
determined. At pH= pKa for an acid, there is an equal amount of conjugate base to acid in
solution. At pH greater than pKa for an acid, the acid will be mostly deprotonated(ionized), At pH
less than 1 unit from a molecule's pKa, the acid will mostly be protonated (deionized)
determined, pH= pKa - ANS Which are True?
If the pH of the solution is known as is the pKa for the acid, the ratio of conjugate base to acid
can be ____. At _____for an acid, there is an equal amount of conjugate base to acid in
solution. At pH greater than pKa for an acid, the acid will be mostly deprotonated(ionized), At pH
less than 1 unit from a molecule's pKa, the acid will mostly be protonated (deionized)
equal amount, - ANS Which are True?
If the pH of the solution is known as is the pKa for the acid, the ratio of conjugate base to acid
can be determined. At pH= pKa for an acid, there is an______ of conjugate base to acid in
solution. At pH greater than pKa for an acid, the acid will be mostly deprotonated(ionized), At pH
less than 1 unit from a molecule's pKa, the acid will mostly be protonated (deionized)
conjugate base ,acid - ANS Which are True?
If the pH of the solution is known as is the pKa for the acid, the ratio of conjugate base to acid
can be determined. At pH= pKa for an acid, there is an equal amount of ____ to _____in
solution. At pH greater than pKa for an acid, the acid will be mostly deprotonated(ionized), At pH
less than 1 unit from a molecule's pKa, the acid will mostly be protonated (deionized)
greater, deprotonated - ANS Which are True?
, If the pH of the solution is known as is the pKa for the acid, the ratio of conjugate base to acid
can be determined. At pH= pKa for an acid, there is an equal amount of conjugate base to acid
in solution. At pH ____ than pKa for an acid, the acid will be mostly _____(ionized), At pH less
than 1 unit from a molecule's pKa, the acid will mostly be protonated (deionized)
less, protonated - ANS Which are True?
If the pH of the solution is known as is the pKa for the acid, the ratio of conjugate base to acid
can be determined. At pH= pKa for an acid, there is an equal amount of conjugate base to acid
in solution. At pH greater than pKa for an acid, the acid will be mostly deprotonated(ionized), At
pH _____ than 1 unit from a molecule's pKa, the acid will mostly be____ (deionized)
FADH2, NADH - ANS Which of the following are reduced forms of electron carriers found in the
body? ____,___
The hydrolysis of ATP to ADPis easier to reverse. - ANS Why is ATP used as our energy
currency molecule if its hydrolysis can yield -32.2kJ/mol while phosphoenolpyruvate yields-61.9
kJ/mol when the phosphate is broken off instead? _____
Increased stabilization of the product due to the gain of resonance stabilization - ANS What is
one contributing factor that energetically favors the hydrolysis of ATP to ADP? ____
The free energy value is positive - ANS Which of the following statements is true of a
non-spontaneous process? ____
thermodynamically favorable under defined non-standard conditions. - ANS The delta G of a rxn
can be used to calculate whether a rxn is _____
Glut, Arg, Asp, Glu, Lys, Asp - ANS The following single letter code of amino acids represent
which set of full names at physiological pH? QRNEKD
____,______,____,___,___,___
Protonate S195 - ANS The 102nd amino acid in chymotrypsin serves a very important role in
the catalytic triad discussed in class. Which of the following does it do? ____
Amino acid < protein < ribosome < mitochondrion - ANS Which one of the following has the
cellular components arranged in order of increasing size?
The tertiary structure of the protein would be less stable after the mutation - ANS at
physiological pH glu acid's R is deprotonated, while alanine's R group is charge neutral. If a glu
acid that is critical to the tertiary structure of a protein is mutated to ala, what is the predicted
effect? ____