100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Pharmacology Antidepressants Quiz | Questions And Answers Latest {} A+ Graded | 100% Verified $13.48   Add to cart

Exam (elaborations)

Pharmacology Antidepressants Quiz | Questions And Answers Latest {} A+ Graded | 100% Verified

 1 view  0 purchase
  • Course
  • Top Academic Resources 2024/2025
  • Institution
  • Top Academic Resources 2024/2025

Pharmacology Antidepressants Quiz | Questions And Answers Latest {} A+ Graded | 100% Verified

Preview 2 out of 8  pages

  • August 24, 2024
  • 8
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • Top Academic Resources 2024/2025
  • Top Academic Resources 2024/2025
avatar-seller
oneclass
Pharmacology Antidepressants Quiz | Questions And Answers Latest {2024- 2025} A+
Graded | 100% Verified


Types of Depression - major, chronic, atypical, bipolar, manic, seasonal affective disorder



Major Depression - recurring and disabling. Symptoms must last for at least two weeks and impair one's
ability to interfere with a person's ability to work, sleep, study, eat, and enjoy once-pleasurable
activities.



Chronic Depression - - less disabling than major depression, but symptoms can last longer, sometimes
being unhappy for two years. More common in women, affects 10.9 million people.



Atypical depression - rather than the other two, is characterized less by pervasive sadness and more by
overeating, oversleeping, sensitivty to rejection



Manic depression - depression oscillates between major depression and epsidoes of mania/ extreme
elation



Seasonal Affective Disorder - - often occurs wehre winters are short or there is a big change in the
amount of sunlgiht, and often treated with light therapy.



Diagnosis of Depression requires must have one of the top two and at least ____ other symptoms nearly
_____ for at least ___ weeks - MUST HAVE one of the top two

AT LEAST five of the other symptoms

Nearly DAILY

For at least TWO WEEKS



Causes of Depression - Genetics, death/psychosocial stress, medicine side effect



What kinds of drugs can cause depression as a side effect - Drugs like antihypertensives, oral
contraceptives, and Accutane for acne can cause depression

, Dosing schedule of antidepressants - what constitutes an adequate trial - slow low and increase rapidly
to target dose, maintain for 4-8 weeks



Which have known therapeutic drug levels? - Imipramine, desipramine, nortriptyline, amitriptyline
(possibly) all other unknown currently



How do antidepressants work? - synaptic pharmacology



Acute effect involves reuptake or degradation of ____ in the post synaptic ______ receptor -
monoamines in alpha 1



Chronic effects involve down regulation of _____ synaptic receptors, and alteration of protein synthesis
and messenger systems - post



The monoamine hypothesis suggests what? - Monoamine hypohtesis suggests that small amount of
neurotransmitter causes depression



the Receptor Sensitivity Hypothesis suggests what? - Supersensitivity and up-regulation of post-synaptic
receptors leads to depression



the sensitivity of the postsynaptic receptors to the NE and 5-HT neurotransmitters fluctuate to have
periods of hypersensitivity and also decreased response



Pharmacokinetics of antidepressants are what? - Absorption is rapid

Metabolism: extensive 1st pass

Oxidation, hydroxylation, demethylation

5% = "slow acetylators"

Protein bound: 90 - 95%



***a lot of drug interactions since protein bound

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller oneclass. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $13.48. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

62890 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$13.48
  • (0)
  Add to cart