BMS 430 Exam 3 Questions & Answer 100%
Verified
What is different about birds genetic sex? Correct answer-XX is male
XY is female
What is different about the genetic sex of fish? Correct answer-Can be
either (XX or XY) depending on species
Sometimes determined by temperature
Some have the ability to switch
What gene does the Y chromosome carry which is important in sex
differentiation? Correct answer-SRY gene
Testosterone---->DHT by Correct answer-enzyme 5 alpha reductase
Testosterone---->estradiol by Correct answer-aromatase enzyme
PDG Correct answer-are stem cells in the gonads
What is the SRY gene? Correct answer-Sex Reversal Y gene
, BMS 430 Exam 3 Questions & Answer 100%
Verified
AKA as TDF (testis determining factor)
How does the SRY gene differentiate gonads? Correct answer-Turns on
Sox 9, a box set of genes which influences sertoli and leydig cells to differentiate
the gonads into testis
What do the Sertoli cells produce under the influence of the SRY gene?
Correct answer-MIF - mullarian-inhibiting factor
Causes the mullerian duct regression
What do the Leydig cells produce under the influence of the SRY gene?
Correct answer-Testosterone
- development of Wolffian ducts
(Vas deferens, seminal vesicles, epidymis)
- DHT >> penis and scrotum development
What duct is preprogrammed to develop? Correct answer-Mullerian
What hormone masculinizes the brain? Correct answer-estradiol
, BMS 430 Exam 3 Questions & Answer 100%
Verified
What protein in females prevents estradiol from crossing the BBB and
masculinizing the brain? Correct answer-alpha fetoprotein produced by
the liver binds and degrades estradiol
Why can male brains be masculinized? Correct answer-Testosterone isn't
bound by alpha fetoprotein so it crosses the BBB, attaches to receptors and is
converted into estradiol
Once masculinized, the male brain converts into what three parts?
Correct answer-Pulse generator
Aggression center
Libido center
Describe the pulse generator Correct answer-- releases GnRH in pulses 90
min
- negative feedback from:
progesterone
estradiol
, BMS 430 Exam 3 Questions & Answer 100%
Verified
testosterone
DHT
Describe the aggression center Correct answer-estradiol causes the
production of testosterone receptors
testosterone can trigger aggression
Libido center Correct answer-Maintained with estradiol receptors
T--->Estradiol induces male libido effects
De la Chapelle disorder Correct answer-XX
SRY translocation onto X chromsome
Tract: male
Phenotype: male
Brain: male
under developed--->doesn't act like man
Swyer Disorder Correct answer-XY
Verified
What is different about birds genetic sex? Correct answer-XX is male
XY is female
What is different about the genetic sex of fish? Correct answer-Can be
either (XX or XY) depending on species
Sometimes determined by temperature
Some have the ability to switch
What gene does the Y chromosome carry which is important in sex
differentiation? Correct answer-SRY gene
Testosterone---->DHT by Correct answer-enzyme 5 alpha reductase
Testosterone---->estradiol by Correct answer-aromatase enzyme
PDG Correct answer-are stem cells in the gonads
What is the SRY gene? Correct answer-Sex Reversal Y gene
, BMS 430 Exam 3 Questions & Answer 100%
Verified
AKA as TDF (testis determining factor)
How does the SRY gene differentiate gonads? Correct answer-Turns on
Sox 9, a box set of genes which influences sertoli and leydig cells to differentiate
the gonads into testis
What do the Sertoli cells produce under the influence of the SRY gene?
Correct answer-MIF - mullarian-inhibiting factor
Causes the mullerian duct regression
What do the Leydig cells produce under the influence of the SRY gene?
Correct answer-Testosterone
- development of Wolffian ducts
(Vas deferens, seminal vesicles, epidymis)
- DHT >> penis and scrotum development
What duct is preprogrammed to develop? Correct answer-Mullerian
What hormone masculinizes the brain? Correct answer-estradiol
, BMS 430 Exam 3 Questions & Answer 100%
Verified
What protein in females prevents estradiol from crossing the BBB and
masculinizing the brain? Correct answer-alpha fetoprotein produced by
the liver binds and degrades estradiol
Why can male brains be masculinized? Correct answer-Testosterone isn't
bound by alpha fetoprotein so it crosses the BBB, attaches to receptors and is
converted into estradiol
Once masculinized, the male brain converts into what three parts?
Correct answer-Pulse generator
Aggression center
Libido center
Describe the pulse generator Correct answer-- releases GnRH in pulses 90
min
- negative feedback from:
progesterone
estradiol
, BMS 430 Exam 3 Questions & Answer 100%
Verified
testosterone
DHT
Describe the aggression center Correct answer-estradiol causes the
production of testosterone receptors
testosterone can trigger aggression
Libido center Correct answer-Maintained with estradiol receptors
T--->Estradiol induces male libido effects
De la Chapelle disorder Correct answer-XX
SRY translocation onto X chromsome
Tract: male
Phenotype: male
Brain: male
under developed--->doesn't act like man
Swyer Disorder Correct answer-XY
