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CMN 568 Unit 3 questions with complete
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What \are \the \3 \characteristics \of \Asthma \- \(correct \answer) \-Bronchoconstriction

Airway \Inflammation

Reversible \airflow \limitation

Which \inhaled \anticholinergic \is \best \used \for \asthma \pt. \w/an \intolerance \to \beta \agonist \or \
w/ \bronchospasms \due \to \beta \blocker \meds? \- \(correct \answer) \-Ipratropium \Bromide

What \is \the \primary \tx \for \pt. \w/moderate \to \severe \asthma \exacerbations \who \do \not \respond \
promptly \and \completely \to \SABA? \- \(correct \answer) \-Systemic \Corticosteroids

Which \bacterial \infections \predispose \exacerbations \of \asthma \- \(correct \answer) \-M. \
Pneumoniae \and \C. \Pneumoniae

Is \routine \use \of \antimicrobials \recommended \for \acute \exacerbations \of \asthma \- \(correct \
answer) \-No, \only \use \when \likelihood \of \acute \bacterial \respiratory \tract \infection

Name \short \acting \beta \agonist \- \(correct \answer) \-albuterol, \levalbuterol, \bitolerol, \pirbuterol, \
terbutaline

What \does \a \SABA \do? \- \(correct \answer) \-acts \directly \by \relaxing \bronchial \smooth \muscles.

What \do \long-term \pharmacologic \agents \accomplish \for \asthma \pt. \- \(correct \answer) \-act \
primarily \to \attenuate \airway \inflammation.

Why \take \long-term \pharmacologic \agents \for \asthma \daily? \- \(correct \answer) \-to \achieve \and \
maintain \control \of \persistent \asthma \independent \of \symptoms.

What \does \the \NAEPP \recommend \as \the \cornerstone \of \daily \treatment \of \persistent \
asthma? \- \(correct \answer) \-daily \anti-inflammatory \therapy \with \inhaled \corticosteroids

Role \of \corticosteroids \with \asthma \- \(correct \answer) \-Reduce \inflammation \(acute \and \chronic) \
= \improved \airflow, \decreased \airway \hyper-responsiveness \and \fewer \asthma \exacerbations, \and \
potentiate \the \action \of \beta-adrenergic \agonist.

,1st. \line \treatment \agent \for \all \pt \w/persistent \asthma \(long \term \controller) \- \(correct \
answer) \-Inhaled \Corticosteroids

How \often \to \most \patient \use \inhaled \corticosteroids? \- \(correct \answer) \-Twice \daily \to \
provide \adequate \control.

How \long \can \it \take \to \see \maximum \response \of \inhaled \corticosterioids? \- \(correct \answer) \-
Months

What \can \a \patient \do \to \reduce \side \effects \of \inhaled \corticosteroids? \- \(correct \answer) \-Rinse
\mouth \after \each \use


A \patient \has \an \exacerbation \of \asthma, \what \is \the \most \effective \treatment \to \achieve \
prompt \control? \- \(correct \answer) \-Systemic \(oral) \corticosteroids

Dose \of \oral \corticosteroids \for \children \during \exacerbation \of \asthma \- \(correct \answer) \-1-2 \
mg/kg/day. \

Can \be \either \a \single \dose \or \divided \BID. \

MAX \60 \mg/day

Dose \of \oral \corticosteroids \for \adults \during \exacerbation \of \asthma \- \(correct \answer) \-40-60 \
mg/day

either \as \a \single \dose \of \divided \BID

Duration \of \treatment \of \oral \corticosteroids \for \asthma \exacerbation \- \(correct \answer) \-3-10 \
days \or \until \symptoms \resolve \

(no \evidence \that \tapering \dose \of \PO \steroids \prevents \relapse)

When \treating \exacerbation \of \asthma, \what \is \the \preferred \treatment \plan? \- \(correct \
answer) \-Alternate \days \rather \than \daily \treatment.

What \additional \medications \are \required \to \be \given \concurrent \with \systemic \corticosteroids \
to \prevent \corticosteroid \induced \bone \mineral \loss? \- \(correct \answer) \-Vitamin \D \and \Calcium

Should \systemic \corticosteroids \be \rapidly \discontinued? \- \(correct \answer) \-No, \to \prevent \
adrenal \insufficiency

Name \some \mediator \inhibitors \to \treat \asthma \- \(correct \answer) \-Cromolyn \sodium \and \
nedocromil

What \is \the \mechanism \of \action \of \mediator \inhibitors? \- \(correct \answer) \-prevent \asthma \
symptoms, \improve \airway \function \in \pt \w/mild \persistent \of \exercise \induce \asthma

When \are \mediator \inhibitors \effective? \- \(correct \answer) \-Before \allergen \exposure \or \exercise

, Do \not \relieve \asthmatic \symptoms \once \present.

Name \the \Long \acting \beta \2 \agonist \(LABA) \for \asthma \- \(correct \answer) \-Salmeterol \and \
Formoteol

How \are \LABA's \delivered? \- \(correct \answer) \-dry \powder

What \are \LABA's \used \for \- \(correct \answer) \-Long \term \prevention \of \asthma \symptoms

Nocturnal \symptoms

Prevention \of \exercise \induced \bronchospasm

Should \LABA \be \used \as \monotherapy \- \(correct \answer) \-NO

linked \to \fatal \asthma \when \used \alone

has \no \anti-inflammatory \effects- \so \use \w/a \corticosteroid.

What \does \LABA \+ \low \or \medium \dose \of \corticosteroids \given \together \provide \for \the \
patient. \- \(correct \answer) \-The \equivalent \to \what \would \be \if \doubled \the \inhaled \
corticosteroid.

Name \the \action \of \anticholinergic \agents, \short \acting \muscarinic \agents \(SAMA) \and \long \
acting \muscarinic \agents \(LAMA) \- \(correct \answer) \-Reverse \vagally \medicated \bronchospasm \
but \NOT \allergen \or \exercise \induced \broncospasms

Is \Ipratropium \bromide \(SAMA) \as \effect \as \a \SABA \for \relief \of \acute \bronchospasm \- \(correct \
answer) \-No

What \is \the \benefit \to \adding \Tiotropium \to \therapy \bronchodilator \(salmeterol) \or \inadequately \
controlled \low-dose \inhaler. \- \(correct \answer) \-Improves \lung \function \and \reduces \frequency \of \
asthma \exacerbations.

Name \the \phosphodiesterase \inhibitor \used \for \asthma \- \(correct \answer) \-theophylline

What \is \theophylline \used \for \in \a \pt \w/ \asthma? \- \(correct \answer) \-mild \bronchodilation

What \is \the \mechanism \of \action \of \theophylline \for \asthma \- \(correct \answer) \-anti-
inflammatory \and \immunodilator \properties \which \enhance \mucociliary \clearance \and \strengthen \
diaphragmatic \contractility.

Why \are \drug \levels \of \Theophylline \monitored? \- \(correct \answer) \-Due \to \narrow \therapeutic \
ranges.

Name \the \leukotriene \modifiers \for \asthma \- \(correct \answer) \-Zileutonn, \zafirlukast, \montelukast

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