GMS6551 Final Exam Study Guide | Questions And Answers Latest {2024- 2025} A+
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Lead compound - The first compound discovered to have the desired activity
Molecular docking - The least expensive method of discovering a drug
Structure activity relationship - The process of step-wise alteration of a drug to improve its properties
Research and development expenses of pharma in 2016 - Approximately 60 billion dollars
Pharmacokinetics - The branch of pharmacology that studies the effect of the body on drugs
Pharmacogenetics - The branch of pharmacology that studies how patients respond differently to drugs
Pharmacodynamics - The branch of pharmacology that studies the desired effect of drugs on the body,
usually at the molecular level
Toxicology - The branch of pharmacology that studies adverse effects of drugs on the body
Excretion - The branch of pharmacology that deals with the elimination of drugs from the body
Chemical name for a popular OTC painkiller - N-acetyl-para-aminophenol
Proprietary name for a popular OTC painkiller - Tylenol
Non-proprietary name for a popular OTC painkiller - Acetaminophen
OTC drugs in the U.S. - Diphenhydramine, Loperamide
, Prescription drugs in the U.S. - Codeine, Levothyroxine, Tadalafil
Schedule of controlled substance for low-dose codeine - III
Stage of translational research utilizing FDA approved drug - T3
Parts of translational research with critical patient involvement - Public Health, Pre-Clinical Research,
Clinical Research, Clinical Implementation
Transition between controlled settings and real-world settings in translational research - T2-T3
Type of drug most likely to be given orally - Small molecule
Class of overnight contact lenses - Class III
Process of pre-clinical testing using human tumor placed under the skin of a mouse - Patient-derived
xenograft
Regulatory body for carrying out a similar study in rats - IACUC
Primary purpose of a Phase I clinical trial - Treatment safety
Action required by a patient before enrolling in a phase I clinical trial - Informed consent
Type of clinical trial where MTD is most likely determined - Phase 1
Government agency regulating phase I clinical trials in the United States - FDA
Type of clinical trial for a new painkiller in terminal cancer patients in hospice - Quality of life trial
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