Study Guide Unit 1 NU 545
What is metabolic absorption? - ANS The process of moving nutrients from the intestines into
the bloodstream.
What uses oxygen to remove hydrogen atoms in an oxidative reaction? - ANS Peroxisomes
During cell injury what is released that is capable of cellular autodigestion? - ANS digestive
enzymes from lysosomes
Cellular Injury Chpt. 2 Power Point
A nurse knows that free radicals may be produced by - ANS metabolism of exogenous
chemicals or drugs
Where is the genetic info contained in the cell? - ANS The cell nucleus (DNA)
Cell membranes contain which major chemical components - ANS phospholipids, cholesterol,
proteins and carbohydrates
What allows potassium to diffuse in and out of cells? - ANS Aldosterone, insulin, and
epinephrine
What is cellular adaptation? - ANS The cell's response to escape and protect itself from injury
Which of the following statements is correct regarding pathologic hyperplasia ?
1.) Produces abnormal proliferation of abnormal cells.
2.) Is it an adaptive mechanism that enables organ regeneration?
3.) Increases cell size
4.) May occur in response to growth factors. - ANS Produces abnormal proliferation of
abnormal cells
What is dysplasia? - ANS Abnormal changes in the size, shape, and organization of mature
cells. Does not indicate cancer. ( Can also be called atypical hyperplasia)
What is metaplasia? - ANS reversible change in which one adult cell type is replaced by
another adult cell type
Which of the following is true about alcohol (ethanol)?
1.) Is metabolized via the microsomal P-450.
2.) Is primarily metabolized and excreted by the kidneys.
3.) Increases activation of methionine, an essential amino acid.
, 4.) Can produce hypermagnesemia with chronic use. - ANS Is metabolized via the microsomal
P-450
What protects the cell from injury? - ANS Cellular Adaptation
What causes ischemic reperfusion injury? - ANS oxidative stress
radicals that cause membrane damage and
mitochondrial calcium overload
Mitochondrial permeability transition pose
Mechanism of cellular injury? - ANS Tissue transplantation
Ischemic syndromes: myocardial, hepatic, intestinal, cerebral, renal, stroke
In cirrhosis, what does cholesterol have to do with the erythrocytes? - ANS
What are two major sources of mercury? - ANS Fish and healthcare equipment
What is a platelet-derived growth factor? - ANS A family of molecules released from platelets
(tiny pieces of cells that are found in the blood and that help the blood clot). Forms of
platelet-derived growth factor help to heal wounds and to repair damage to blood vessel walls.
They also help blood vessels grow. Also called PDGF.
What is cell communication? How does it occur? - ANS Cell communication is the process by
which a cell detects and responds to signals in its environment. Cells communicate through their
own language of chemical signals. Different compounds, such as hormones and
neurotransmitters, act like words and phrases, telling a cell about the environment around it or
communicating messages.
What does excess urate (uric acid)cause? - ANS Gout
What essential nutrients are required for normal cell function? - ANS proteins, carbs, lipids,
vitamins, and minerals.
What are some examples of immunological and inflammatory substances that lead to injury? -
ANS (Phagocytic cells- ability to ingest foreign particles)
Histamine
Antibodies
Lymphokines
Complement
Proteases
What is chemical signaling? - ANS interaction between receptors and ligands (chemical
messengers) that cause changes in cellular activities
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