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PSIO 303 Exam Practice Test with Complete Solutions

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PSIO 303 Exam Practice Test with Complete Solutions Which of the following is an accurate statement about signal transduction? A. A chemical messenger produced by one cell in a tissue that acts on an adjacent cell in the tissue is an example of endocrine communication. B. Only the amino acid...

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  • August 28, 2024
  • 74
  • 2024/2025
  • Exam (elaborations)
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  • PSIO 303
  • PSIO 303
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©SOPHIABENNET@2024/2025 Wednesday, August 21, 2024 12:13 PM



PSIO 303 Exam Practice Test with
Complete Solutions

Which of the following is an accurate statement about signal
transduction?



A. A chemical messenger produced by one cell in a tissue that acts
on an adjacent cell in the tissue is an example of endocrine
communication.



B. Only the amino acids tyrosine, serine, and alanine in signaling
proteins undergo phosphorylation and dephosphorylation.



C. Phosphorylation of an intracellular protein can result in either
activation or inactivation of that protein.



D. A doubling of hormone binding to its plasma membrane
receptors will cause a doubling of a cellular response - Answer✔️✔️-
C. Phosphorylation of an intracellular protein can result in either
activation or inactivation of that protein.

Oxidative stress...




1

, ©SOPHIABENNET@2024/2025 Wednesday, August 21, 2024 12:13 PM


A. is characterized by excess ROS production.



B. is associated with cell damage and impaired cell signaling.



C. can be caused by elevated blood glucose levels.



D. All of the above. - Answer✔️✔️-D. All of the above.

Which of the following second messengers is NOT produced via a
GPCR coupled with the given G-protein?



1. Gs: cAMP



2. Gi: cGMP



3. Gq: DAG and Ca2+



4. Gt: GMP - Answer✔️✔️-2. Gi: cGMP

The infusion of an inhibitor of eNOSinto an individual would have
what effect?




2

, ©SOPHIABENNET@2024/2025 Wednesday, August 21, 2024 12:13 PM


1. Increase blood flow and glucose transport into skeletal muscle



2. Decrease blood flow and glucose transport into skeletal muscle



3. Have no effect on blood flow and glucose transport into skeletal
muscle - Answer✔️✔️-2. Decrease blood flow and glucose transport
into skeletal muscle

Insulin resistance of glucose disposal in skeletal muscle is
associated with all of the following EXCEPT:



A. Impaired vasodilation in arterioles due to excessive
eNOSactivation in smooth muscle cells



B. Decreased tyrosine phosphorylation of IR and IRS-1



C. Enhanced IRS-1 serine phosphorylation by PKC θinitiated by
excess plasma FFA



D. Less plasma membrane GLUT-4 due to decreased GLUT-4
translocation - Answer✔️✔️-A. Impaired vasodilation in arterioles due
to excessive eNOSactivation in smooth muscle cells




3

, ©SOPHIABENNET@2024/2025 Wednesday, August 21, 2024 12:13 PM


Insulin secretion from β-cells requires all of the following EXCEPT:



A. ATP production (primarily from glucose oxidation in
mitochondria).



B. ATP-mediated opening of K+-channels and membrane
hyperpolarization.



C. Opening of voltage-gated Ca2+-channels and Ca2+release from
the ER.



D. Exocytosis of secretory granules and release of insulin from the
β-cell - Answer✔️✔️-B. ATP-mediated opening of K+-channels and
membrane hyperpolarization.

Based on information presented in class, when would be the
optimal time to treat an individual with sulfonylureas?



A. Before development of insulin resistance and compensatory
hyperinsulinemia



B. Right after insulin resistance and hyperinsulinemia first develop




4

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