The three major routes of excretion are: - correct answer ✔✔Urinary excretion, fecal excretion, and
exhaled air
The quantity of a substance administered to an individual over a period of time or in several individual
doses is known as the: - correct answer ✔✔Total dose
Fractionation of a total dose so that the total amount administered is given over a period of time usually
results in: - correct answer ✔✔Decreased toxicity
An internal dose refers to - correct answer ✔✔the portion of an exposure that becomes internalized in
the body.
The concentration and toxicity of a chemical in the body are affected by: - correct answer ✔✔- route of
entry into the body.
individual sensitivity.
- duration of exposure.
- received dose of the chemical.
When a chemical A and B are administered simultaneously, their combined effects are far greater than
the sum of their effects when given alone. The chemical interaction between chemical A and B can be
described as which of the following? - correct answer ✔✔Synergistic
The usual dosage unit that incorporates the amount of material administered or absorbed in accordance
with the size of the individual over a period of time - correct answer ✔✔mg/kg/day
The dose at which a toxic effect is first encountered is called the: - correct answer ✔✔threshold dose
The Lowest Observed Adverse Effect Level (LOAEL) is the: - correct answer ✔✔Lowest dose at which
there was an observed toxic or adverse effect
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