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NAPLEX Questions: ID 1 with 100% Correct Solutions Latest Update 2024

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Gram positive organisms have a thick cell wall and stain ____. - ANS-Purple or bluish Gram negative organisms have a thin cell wall and result in a ___ color. - ANS-Pink or reddish Identify the bug: gram-positive clusters (1) - ANS-Staphylococcus species Identify the bug: gram-positive coc...

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naplex questions id 1 with 100 correct solutions
naplex questions id 1 stuvia
gram positive organisms have a thick cell wall and

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NAPLEX Questions: ID 1 with 100%
Correct Solutions Latest Update 2024

Gram positive organisms have a thick cell wall and stain ____. - ANS-Purple or bluish

Gram negative organisms have a thin cell wall and result in a ___ color. - ANS-Pink or
reddish

Identify the bug: gram-positive clusters (1) - ANS-Staphylococcus species

Identify the bug: gram-positive cocci in pairs and chains (3) - ANS-Strep. pneumoniae
(pairs), Streptococcus species, Enterococcus species

Identify the bug: gram-positive rods (1) - ANS-Listeria monocytogenes

Identify the bug: gram-positive anaerobes (3) - ANS-Peptostreptococcus, Actinomyces,
Clostridium

Identify the bug: gram-negative cocci (1) - ANS-Neisseria

Identify the bug: gram-negative anaerobes (2) - ANS-Bacteroides fragilis, Prevotella

Identify the bug: gram-negative coccobacilli (3) - ANS-Acinetobacter baumannii,
Bordetella pertussis, Moraxella catarrhalis

Identify the bug: gram-negative rods that colonize the gut, aka enteric GNRs (5) - ANS-
Proteus mirabilis, E. coli, Klebsiella, Serratia, Enterobacter, Citrobacter

Identify the bug: gram-negative rods that do not colonize the gut (3) - ANS-
Pseudomonas aeruginosa, Haemophilus influenzae, Providencia

,Identify the bug: curved or spiral-shaped gram-negative rods (4) - ANS-H. pylori,
Campylobacter, Treponema, Borrelia

What is an MIC? - ANS-Minimum inhibitory concentration; the minimum concentration of
an antibiotic necessary to kill a bug in 24 hours

If the MIC is ___ than the breakpoint, the antibiotic CAN be used to treat the bacterial
infection - ANS-Less than or equal to

Antibiograms aid in selecting ___ drug therapy and are used to monitor ___ trends over
time - ANS-Empiric; resistance

Name the six common resistant pathogens - ANS-MRSA

VRE (E. faecalis, faecium)

ESBL, CRE E. coli and K. pneumoniae

Acinetobacter baumannii

Pseudomonas aeruginosa

What is intrinsic drug resistance? - ANS-When an antibiotic won't work for a pathogen
purely because of the molecule; vancomycin can't treat E. coli because it's too big to
penetrate the cell wall

What is selection pressure? - ANS-Antibiotics kill off the susceptible bacteria, leaving
behind the more resistant strains to multiply

Name the four beta-lactamase inhibitors - ANS-Clavulanate, sulbactam, tazobactam,
avibactam

Even though all antibiotics are associated with C. diff, this one has a black boxed
warning for it. - ANS-Clindamycin

, Hydrophilic agents have small/large Vds, hepatic/renal elimination, do/do not achieve
intracellular concentrations, increased/decreased clearance and/or distribution in
sepsis, and poor-moderate/excellent PO bioavailability. - ANS-Hydrophilic agents have
small Vds, are renally eliminated, do not achieve intracellular concentrations (not good
against atypicals), increased clearance and/or distribution in sepsis (may need a loading
dose), and poor-moderate bioavailability

Lipophilic agents have small/large Vds, hepatic/renal elimination, do/do not achieve
intracellular concentrations, increased/decreased clearance and/or distribution in
sepsis, and poor-moderate/excellent PO bioavailability. - ANS-Lipophilic agents have
large Vds, hepatic metabolism, achieve intracellular concentrations (active against
atypicals), can be used without dose adjustment in sepsis, and have excellent PO
bioavailability, so PO to IV ratio is often 1:1

Beta-lactams exhibit time-dependent killing, so they are dosed more frequently or at
greater doses - ANS-More frequently. Can also extend infusion time or administer as
continuous infusion.

Aminoglcosides, quinolones, and daptomycin exhibit concentration dependent killing, so
they are dosed more frequently or at greater doses - ANS-At greater doses

What are the three classes of antibiotics that are beta-lactams? - ANS-Penicillins,
cephalosporins, and carbapenems

What is the MOA of beta-lactams? - ANS-Inhibit bacterial cell wall synthesis

Are beta-lactams time-dependent or concentration-dependent killers? - ANS-Time-
dependent

Natural penicillins are mainly active against gram ___ like ___ with little activity against
gram ___. - ANS-Positives like Streptococci and other mouth flora; little activity against
gram negatives.

Amoxicillin and ampicillin cover gram positives like __ and __, plus gram-negative bacilli
HNPEK and gram-negative anaerobes (B. Fragilis). What are those anyway? - ANS-
Streptococci and enterococci

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NAPLEX Questions: ID 1 with 100% Correct Solutions Latest Update 2024

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