,In 95% of children of delayed puberty, the problem is caused by:
a.
Disruption in the hypothalamus
c.
Deficit in estrogen or testosterone
b.
Disruption of the pituitary
d.
Physiologic hormonal delays - Answer: D
In 95% of children with delayed puberty, the delay is physiologic; that is, hormonal levels are normal and
the hypothalamic-pituitary-gonadal (HPG) axis is intact, but maturation is slowly happening. This option
is the only answer that accurately describes the most common cause of delayed puberty.
What is the first sign of puberty in girls?
a.
Breast enlargement
c.
Menstruation
b.
Growth of pubic hair
d.
Vaginal discharge - Answer: A
Of the options available, the first sign of puberty in girls is usually thelarche or breast development.
Which type of precocious puberty causes the child to develop some secondary sex characteristics of the
opposite sex?
a.
Mixed
c.
Isosexual
,b.
Incomplete
d.
Homosexual - Answer: A
Mixed precocious puberty, which is virilization of a girl or feminization of a boy, causes the child to
develop some secondary sex characteristics of the opposite sex. This option is the only answer that
accurately identifies the type of precocious puberty described.
The release of which chemical mediator causes primary dysmenorrhea?
a.
Leukotrienes
c.
Bradykinin
b.
Prostaglandins
d.
C-reactive protein - Answer: B
Primary dysmenorrhea is painful menstruation associated with the release of prostaglandins in
ovulatory cycles. This option is the only answer that accurately identifies the chemical mediator
associated with dysmenorrhea.
Considering the pathophysiologic characteristics of primary amenorrhea, what anatomic structure is
involved in compartment II?
a.
Ovary
c.
Hypothalamus
b.
Anterior pituitary
d.
, Vagina - Answer: A
Compartment II disorders involve only the ovary.
Considering the pathophysiologic characteristics of primary amenorrhea, what anatomic structure is
involved in compartment IV?
a.
Vagina
c.
Ovary
b.
Hypothalamus
d.
Anterior pituitary - Answer: B
Of the options available, only compartment IV disorders include central nervous system (CNS)
conditions, in particular hypothalamic disorders.
Which condition is considered a clinical cause of amenorrhea?
a.
Disorder in the endometrium
c.
Lack of physical exercise
b.
Obstruction of the fallopian tubes
d.
Failure to ovulate - Answer: D
Depressed ovarian hormone levels, which are associated with a variety of clinical disorders, also cause
amenorrhea by preventing ovulation. This option is the only answer that accurately identifies a clinical
cause of cycle irregularities.
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