ASCP HEMATOLOGY EXAM REVIEW 2024/ACTUAL
250 EXAM QUESTIONS WITH CORRECT DETAILED
AND VERIFIED ANSWERS/100% CORRECT/LATEST
UPDATE 2024-2025
Name the locations of active marrow in adults: - RIGHT ANS:->>>sternum, skull,
ribs, pelvis, vertebrae
Where does hematopoiesis take place during the first 2 months of gestation? -
RIGHT ANS:->>>yolk sac
Where does the majority of hematopoiesis take place during the 2nd through 7th
month of gestation? - RIGHT ANS:->>>spleen
When does the bone marrow take over hematopoiesis? - RIGHT ANS:->>>after
birth
What are the stages in order of the erythrocyte lineage? - RIGHT ANS:-
>>>(1)rubriblast, (2)prorubricyte, (3)rubricyte, (4)metarubricyte, (5)reticulocyte,
(6)erytrocyte
What are the stages in order of the granulocyte (neutrophil, eosinophil, basophil)
,lineage? - RIGHT ANS:->>>(1)myeloblast, (2)promyelocyte, (3)myelocyte,
(4)metamyelocyte, (5)band, (6)segmented (7)eos/baso
What are the stages in order of the macrophage lineage? - RIGHT ANS:-
>>>(1)monoblast, (2)promonocyte, (3)monocyte, (4)macrophage
What are the stages in order of the platelet lineage? - RIGHT ANS:-
>>>(1)megakaryoblast, (2)promegakaryocyte, (3)megakaryocyte, (4)platelet
What are the stages in order of the lymphocyte lineage? - RIGHT ANS:-
>>>(1)lymphoblast, (2)prolymphocyte, (3)lymphocyte
Which growth factors stimulate the erythrocyte lineage? - RIGHT ANS:->>>GM-
CSF, EPO, IL-3
Which growth factors stimulate the granulocyte lineages? - RIGHT ANS:->>>GM-
CSF, IL- 3
Which growth factors stimulate the platelet lineage? - RIGHT ANS:->>>GM-CSF,
IL-3, TPO
Which growth factors stimulate the lymphocyte lineage? - RIGHT ANS:->>>IL-2,
,IL-4, IL-6, IL-7
Which protein functions in the transport of Fe? - RIGHT ANS:->>>transferrin
What is the major storage form of Fe? - RIGHT ANS:->>>ferritin
What is the long-term (H20) insoluble Fe storage form called? - RIGHT ANS:-
>>>hemosiderin
Excess Iron is stored where? What does this cause? - RIGHT ANS:->>>tissues and
body organs, hemosiderosis, hemochromatosis
Porphyrias are attributed to? - RIGHT ANS:->>>excessive formation of porphrins
due to blockages in any enzymatic step in the heme synthesis pathway.
Red or port wine colored urine can be seen in which condition related to the build up
of heme precursors? - RIGHT ANS:->>>porphyria
Neuropsychiatirc symptoms are seen when a build up of which precursors occurs? -
RIGHT ANS:->>>early precursors (Delta-aminolevulinic acid/Porphobilinogen)
Cutaneous symptoms such as photo-sensitivity and facial hair are seen when a build
up of which precursors occurs? - RIGHT ANS:->>>later precursors
(uroporphyrinogen/coproporphyrinogen, protoporphyrin/heme)
, Synthesis of heme requires what two components? - RIGHT ANS:->>>iron,
protoporphyrin
What are the heme precursors in order of synthesis? - RIGHT ANS:->>>(1)delta-
aminolevulinic acid, (2)porphobilinogen, (3)uroporphyrinogen,
(4)coproporphyrinogen, (5)protoporphyrin, (6)heme
What type of hemoglobin is seen primarily in newborns? - RIGHT ANS:->>>Hgb F
What type of hemoglobin is seen primarily in adults? - RIGHT ANS:->>>Hgb A2
What type of hemoglobin is rarely seen in adults as well as newborns? - RIGHT
ANS:->>>Hgb A
What hemoglobin types are seen in embryos but not in adults or newborns? - RIGHT
ANS:->>>gower I, gower II, portland
All non-embryonic hemoglobin types are comprised of what type of globin chain? -
RIGHT ANS:->>>alpha
Hemoglobin A2 is composed of what types of globin chains? - RIGHT ANS:-
