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Exam 2 - ExRx for those with Cardiovascular and Pulmonary Diseases Exam Study Guide with Complete Solutions $9.99   Add to cart

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Exam 2 - ExRx for those with Cardiovascular and Pulmonary Diseases Exam Study Guide with Complete Solutions

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Exam 2 - ExRx for those with Cardiovascular and Pulmonary Diseases Exam Study Guide with Complete Solutions Injury to the endothelium (many causes) → ....... -2 main causes? - Answer️️ -endothelial dysfunction... -high Blood Pressure (results in higher turbulent flow - excessive pounding...

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  • August 29, 2024
  • 48
  • 2024/2025
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SophiaBennett
©SOPHIABENNETT@2024-2025 Sunday, August 25, 2024 2:42 PM


Exam 2 - ExRx for those with Cardiovascular
and Pulmonary Diseases Exam Study Guide
with Complete Solutions

Injury to the endothelium (many causes) → .......

-2 main causes? - Answer✔️✔️-endothelial dysfunction...

-high Blood Pressure (results in higher turbulent flow - excessive pounding
on endothelial cells)

-glycosolated haemoglobin = HbA1c (% of Hb that has glycogen attached)
(spikes of the glucose rake the endothelial layer causing it to become
damaged)

Endothelial dysfunction causes .....

-5 step process? - Answer✔️✔️--disturbed blood flow which causes

-endothelial cell activation (since the cells have been damaged)

-recruitment of inflammatory cells to vessel wall (WBCs arrive here)

-cell signaling facilitates LDL retention in tunica intima (LDL is used to
help the endothelial layer heal but if too much LDL is retained, it can lead
to blood clotting).

-oxidative modification by ROS and inflammatory enzymes




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, ©SOPHIABENNETT@2024-2025 Sunday, August 25, 2024 2:42 PM

What is the problem with hypertension/diabetes in terms of the effect on
endothelial dysfunction? - Answer✔️✔️-Can cause accumulation of lipids as
endothelial layer is constantly being damaged

Accumulation of lipids

-5 step process? - Answer✔️✔️-↳ monocytes become macrophages which try
to digest mLDL. When the macrophages cannot digest any more mLDL,
they become foam cells

↳endoplasmic reticulum stress triggers foam cell apoptosis (organised
programmed cell death)

↳Efferocytic program (burying of cells) cannot keep up with source of
apoptotic formation

↳Apoptotic cells that aren't being destroyed properly undergo secondary
necrosis forming necotic core = atherosclerotic plaque (purple blob on my
pic)

•Unstable and vulnerable to disruption.

2 effects of atherosclerotic plaques developing - Answer✔️✔️--can cause
clotting at site of plaque in response to internal bleeding

-plaque can break off and travel in blood to cause clotting elsewhere

Where in the blood vessels are clots most likely? - Answer✔️✔️-Where there
is branching?

Cardiac Rehabilitation (CR)



2

, ©SOPHIABENNETT@2024-2025 Sunday, August 25, 2024 2:42 PM

• Ex and lifestyle interventions

• Currently, ........... insurance reimburses for CR for MI/acute coronary
syndrome, CABG, PTCA, stable angina, valve repair/replacement, CHF,
and heart transplant.

• ..... and ..... (2 phases of CR) - Answer✔️✔️--Medicare/private

-Inpatient and Outpatient

Inpatient Cardiac Rehabilitation: Guidelines

• Current clinical status ..........

• Mobilization

• Identification and provision of information regarding modifiable .....
factors and .....

• Discharge planning with a home ..... and .....

• Referral to .......... CR - Answer✔️✔️--assessment

-risk; self-care

-PA; ADL (activities of daily living)

-outpatient

Inpatient Cardiac Rehabilitation: Guidelines

• ........ Assessments

○ Note: diagnosis, current medical status, comorbidities, CVD risk factors,
personalized goals, as well as readiness for PA and learning.


3

, ©SOPHIABENNETT@2024-2025 Sunday, August 25, 2024 2:42 PM

• Supervised daily .......

○ Intermittent ....... or ........ 12-24hrs after MI

⁃ purpose of this?

⁃ Should include documentation of .....

• Individual education on modifiable ..... factors

○ After physical ability and psychological willingness is ...... - Answer✔️✔️-•
Clinical

• ambulation (moving/walking)

○ sitting; standing

⁃ "prevent" exercise performance decrements

⁃ vital signs

• risk

○ known

Inpatient Cardiac Rehabilitation: Guidelines

• Before discharge:

○ Need to know ........ activities (Heavy lifting, climbing stairs, yard work,
etc)

○ Need to have a ..... plan of exercise

○ Individuals should know how to identify ...... signs and symptoms



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