receptors
Generaldefenitionacellproteinmembraneintracellularthata ligandbinds iii
modifiedsensoryneuron apartof modified
sensoryreceptor
sensoryneuron 3anyotherspecializedcellthatconverts a stimulus membraneboundreceptor
intoreceptorpotentialwhich if it reaches surpasses the
thresholdpotential it initiates impulsein associatednerve
cell specialization
cellsmustcommunicate inmannerthat intracellularreceptors
1 similarcellscanperform acertainfunction
aclassofcellscancommunicate toanotherclasswhentheirneedschange
matron in
sensoryreceptor clinical importance cellmembrane
individualadaptation homeostaticresponse
somatic vs autonomicreflexfunction
3 neurologicalphysicalexamination
byDoctor
note eachsensoryreceptorismostsensative to a specifictype of
stimulation which it convertsintosensoryinformation
actionPotentiale threshold receptorPotential Receptors
C
É
Taing afferentneuro
signaltransduction process of converting a of
neural sensory ligandmediatedmessage stimulus g separatereceptorcell
associatedwith
into a actionpotentialin
peripheralendingof
ng panway
ii a in p c for to initiate biochemicalresponse
structure i a transmembranedomain no a proteinneeded
effectorsystemis intrinsic partof receptor s cytokinereceptors e g Growthhormones prolactin cytokin
mechanism ofaction aligandbind autophosphorination a cause aligandbindstoreceptor athatinducesreceptor tobindto Ic
otherproteinstobephosphoritized3phosphorinationcascadestarts kinasesthatcatalyzesphosphorylation
i Isa 3,4
causes e causes Types of IC receptors
i causes
nuclearreceptors bindtothyroidhormones gene
no 3 Gproteincoupledprotein a subunitactivated a initiates a message transcription hormonereceptor
c omplex bindto HREmmolto
to betransducedviaenzymes e.gadenylatecyclase phospholipase c 2 cytoplasmicreceptors steroidhormones bindto cytoplasmic
3whenmembraneproteinactivated inducereleaseof andmessenger receptors normonreceptorc omplexfreed
frominnistorproteinkeeping
orotherintracellularevents viaatpbindingprotein itincytoplasmmoves tonucleus bindsto re initiate
transcription
Factorsdeterming cell response
receptors Ic location receptormodifications egsteroidreceptors ligandreceptorreactionrate ligandreceptorequilibrium
nowquicklyligand ligandbinds dissociate
ligand influencereceptor
affinity affinityreceptorsneeda
low because and fromreceptor
dissociate samerate
rate d issociateis
ligand onlyquickactionstriggers eg neurotransmision receptorfieldstimulusmaybe receptoraffinity
viseversa highaffinity egsecondmessengercascades inoverlappingreceptorfields
ll mm
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller dakalomatidza. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $2.84. You're not tied to anything after your purchase.