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BIOL 432 Midterm Exam Questions with 100% Correct Answers $12.99   Add to cart

Exam (elaborations)

BIOL 432 Midterm Exam Questions with 100% Correct Answers

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  • Course
  • BIOL 432
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  • BIOL 432

Histone acetylase Correct Answer adds acetyl group onto lysine to remove charge to loosen DNA packaging Changes histones into open conformation and allows for DNA folding and transcription Concentrations influenced by hormones Hepcidin Correct Answer a hormone produced by the liver that ne...

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  • August 30, 2024
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  • 2024/2025
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  • BIOL 432
  • BIOL 432
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BIOL 432 Midterm Exam Questions with
100% Correct Answers
Histone acetylase Correct Answer adds acetyl group onto lysine to remove charge to
loosen DNA packaging

Changes histones into open conformation and allows for DNA folding and transcription

Concentrations influenced by hormones

Hepcidin Correct Answer a hormone produced by the liver that negatively regulates iron
balance in the gastrointestinal tract

Brefeldin A Correct Answer Inhibits Golgi function and secretion of hormones

Used to study hormone build-up

Coat associated protein II Correct Answer aids in vesicle transport from rough
endoplasmic reticulum to cis Golgi network

Coat associated protein I Correct Answer aides in retrograde transport of vesicles from
cis Golgi to trans Golgi and/or rough endoplasmic reticulumev

Pindolo Correct Answer non-selective beta blocker

Beta blocker Correct Answer A medication that reduces the workload of the heart by
slowing the rate of the heartbeat.

Idocyanopindolol (ICYP) Correct Answer is a beta 1 adrenoreceptor agonist and a 5-
HT1A antagonist

1251 radioactive derivative has been used to map the distribution of beta
adrenoreceptors

Agonist Correct Answer a molecule that, by binding to a receptor site, stimulates a
response

Antagonist Correct Answer molecule that blocks a response

GRP-associated protein (GAP) Correct Answer regulates G-alpha subunit and acts as a
scaffold for reassembly of subunits

Beta adrenergic receptor kinase and arrestin Correct Answer desensitizes the G protein
coupled receptor

, Cyclic adenosine monophosphate (camp) Correct Answer intracellular second
messenger that mediates hormone action

Activates protein kinases and opens Ca+2 channels

Produced by adenylyl cyclase activity

Camp response element binding protein (CREB) Correct Answer activated by catalytic
subunit of PKA when it's bound to camp

Enhances transcription

Diacylglycerol (DAG) Correct Answer A second messenger produced by the cleavage of
phosphatidylinositol (4,5) biphosphate

Activates protein kinase C to phosphorylate cytoplasmic membrane proteins and
increase transcription by binding to c-jun and c-fos

1,4,5-triphosphate (IP3) Correct Answer A second messenger produced by the
cleavage of phosphatidylinositol (4,5) biphosphate

Stimulates Ca+2 channels to open
--> Ca+2 causes muscle contraction and transcription

Phosphatidylinositol (4,5) biphosphate Correct Answer cleaved by Phospholipase C
when it's been activated by G alpha q

Forms diacylglycerol and 1,4,5-triphosphate

Cholera Toxin Correct Answer causes ADP-ribosylation of Gαs = inhibits gtpase activity
- AC active longer
In gut = increase water and salt secretion

Growth factor receptor Correct Answer an integral membrane protein that contains a
domain specific for its ligand and also a cytoplasmic domain essential for transmitting
this binding of the ligand to the cytoplasm

Binds growth factor and will cause either
1. Signalling complexes
2. Phosphorylation cascade that ends in increasing transcription

Src homology domains Correct Answer active in the signalling complex formation of the
growth factor receptor

One type recognizes the phosphorylated tyrosine and one recognizes protein domains

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