A group of bioactive, hormone-like chemicals derived from fatty acids that
have a wide variety of biological effects including roles in inflammation,
platelet aggregation, vascular smooth muscle dilation and constriction, cell
growth, protection of from acid in the stomach, and many more.
- Correct Answer - Prostaglandins
Attract phagocytes to area of inflammation
- Correct Answer - chemotactic factors
Inflammatory mediator generated from a complex lipid stored in cell
membranes. Affects a number of cell types, induces platelet aggregation,
activates neutrophils, and is a potent eosinophil chemoattractant.
- Correct Answer - platelet activating factor
A type of white blood cell that engulfs invading microbes and contributes to
the nonspecific defenses of the body against disease.
- Correct Answer - neutrophils
,A type of white blood cell that transforms into macrophages and engulfs
huge numbers of microbes over a long period of time
- Correct Answer - Monocytes
a primary mediator of the humoral immune response that enables the body
to produce inflammation and help the localization of an infective agent
- Correct Answer - complement immunity
system activated by Hageman factor as part of the inflammatory response;
includes bradykinin
- Correct Answer - kinin system
The series of steps beginning with the intrinsic or extrinsic pathways of
coagulation and proceeding through the formation of a fibrin clot
- Correct Answer - coagulation cascade
produced when there is a tissue injury. arachidonic acid is metabolized to
produce inflammatory mediators
- Correct Answer - Arachidonic Acid Pathway
Which two inflammatory mediators are produced in the arachidonic acid
pathway?
- Correct Answer - prostaglandins and leukotrienes
The only selective COX 2 inhibitor still available for use due to blocking of
the inflammatory functions of ___________________________ and risk for
_________ impairment and increase in ______________ events.
Inhibit both Cox-1 and Cox-2 enzymes
-reduces levels of protective
-causes increases gastric acid secretion, __________ bicarbonate
secretion, ____________ mucous secretion leading to formation of gastric
__________.
- Correct Answer - NSAIDs (Non-Selective); prostaglandins; decreased;
decreased; ulcers
Aspirin: Blocks Cox 1, Cox 2 or both?
- Correct Answer - Both
chronic autoimmune inflammatory disease of collagen in skin, joints, and
internal organs
- Correct Answer - systemic lupus erythematosus
inflammation of blood vessels seen in SLE
- Correct Answer - Vasculitis
chronic inflammation of joints; pain, swelling, and stiffening, especially in
the small joints of the hands and feet
- Correct Answer - rheumatoid arthritis
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller NurseMeg. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $10.99. You're not tied to anything after your purchase.
