The mechanisms of communication and control occur w/in autocrine,
paracrine and endocrine. What is autocrine? Right Ans - communcation &
control occurs w/in a cell
The mechanisms of communication and control occur w/in autocrine,
paracrine and endocrine. What is paracrine? Right Ans - communcation
and control occur between local cells
The mechanisms of communication and control occur w/in autocrine,
paracrine and endocrine. What is endocrine? Right Ans - communication &
control occurs between cells located remotely from each other
Describe neg feedback Right Ans - the most common; when a changing
chemical, neural, or endocrine response DECREASES the synthesis and
secretion of a hormone
What hormone release is regulated by? (3) things Right Ans - 1) chemical
factors (BGL level or CA levels) 2) endocrine factors ( a hormone from 1
endocrine gland to another endocrine gland) 3) neural control (when ANS
directly stimulates the insulin secreting cells of the pancreas)
describe pos feedback Right Ans - when a neural, chemical or endocrine
response INCREASES the syntheis and secretion of a hormone
What is another name for the protein hormones Right Ans - peptide
hormone
Are peptide (protein) hormones water soluable? Right Ans - yes
Do water soluable hormones have a short or long half life Right Ans - short
Give 2 ex of lipid soluable hormones Right Ans - cortisol & adrenal
Do free hormones or bound hormones initiate change? Right Ans - free
What is down regulation Right Ans - high concentrations of hormones
decrease the # of receptors (or the affinity)
, Describe water soluable hormones Right Ans - proteins that are polarized
with a high molecular wt and cannot diffuse across the lipid layer of the
plasma membrane
How do water soluable hormones cross the lipid bilayer Right Ans - they
bind with receptors in/on the cell membrane & activate a 2nd messenger to
mediate short acting responses
Do water soluable or lipid soluable diffuse freely across the plasma membrane
Right Ans - lipid
What is a 1st messenger relating to water soluable hormones Right Ans -
when water soluable hormones bind w the plasma membrane receptor
intiates a complex cascade of intracellular effects, this is the 1st messenger
What is the 2nd messenger Right Ans - when the hormone receptor
interaction intiates a signal that generates a small molecule inside the cell, this
is 2nd messenger
What are the 6... 2nd messengers? Right Ans - cAMP, cGMP, Ca++, inositol
triphosphate (IP3), membrane assoc diacylglycerol (DAG), the tyrosine kinase
system
The 1st messengers like insulin, GH, and prolactin directly activates which
2nd messenger? Right Ans - tyrosine kinase family
The 1st messenger binding of angiotensin II and ADH results in synthesis of
which 2nd messengers? Right Ans - DAG or IP3
Which lipid soluable hormone is not synthesized from cholesterol Right
Ans - thyroid hormone
What sort of diffusion does steroid hormones use Right Ans - simple
diffusion bc they are nonpolar, lipophilic
What are the 2 ways hormones affect target cells Right Ans - directly or
permissively
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