FRNSC 421 - EXAM 3 PRACTICE QUESTIONS AND ANSWERS (100% PASS)
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FRNSC421W /FRNSC 420
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FRNSC421W /FRNSC 420
FRNSC 421 - EXAM 3 PRACTICE QUESTIONS AND ANSWERS (100% PASS)
lineage markers - Answer️️ -useful for assisting with the identification of related
individuals separated by generational events
- Y DNA paternally inherited
- mtDNA maternally inherited
Thomas Jefferson case - Answer️️ -Y-S...
FRNSC 421 - EXAM 3 PRACTICE QUESTIONS AND ANSWERS (100% PASS)
lineage markers - Answer✔️✔️-useful for assisting with the identification of related
individuals separated by generational events
- Y DNA paternally inherited
- mtDNA maternally inherited
Thomas Jefferson case - Answer✔️✔️-Y-STR analysis on descendent of Eston
Hemmings to determine if Thomas Jefferson had an affair with his slave Sally
Hemmings
- showed that Eston is related to the Jefferson family, cannot conclusively say it
was Thomas who fathered him
- Tom Woodson, Sally's eldest son, more closely related to Thomas Jefferson's
nephew
applications of Y-STR testing - Answer✔️✔️-- ID & historical cases to verify
relationships
- sexual assault evidence when autosomal STR data produces minor mixed male
profile
- verification of familial testing outcomes, identifying potential paternal relatives
of potential perpetrators
- paternity testing in motherless cases
Y chromosome structure - Answer✔️✔️-has lost ~97% of its genes over the last 300
million years, estimated to lose all genes within the next 10 million
- has male-specific region (MSY) and synonymous non-recombining portion
(NRY)
- lowest gene but highest repetitive sequences/copy number variants
- sex-determining gene in Yp arm
Yfiler - Answer✔️✔️-tests for 16 loci and 17 alleles, including:
- european minimal haplotype loci (MHL) = 8 loci, 9 alleles
- SWGDAM 10 loci
- Yflier has 6 additional loci
- Yfiler Plus has 9 additional loci (10 alleles); 3 highly diverse single allele loci,
and 6 rapidly mutating loci including one multi-locus marker
PowerPlex Y23 - Answer✔️✔️-tests for 22 loci and 23 alleles
- only 2 rapidly mutating loci
DYS385 a/b - Answer✔️✔️-one of 10 SWGDAM loci
- duplicated a and b regions ~40 kb apart facing away from one another
- result of a translocation event duplicating/inverting the locus
- counted as a single locus, use same forward/reverse primers
- results in "heterozygote" profiles when a ≠ b; reported as such, but isn't classified
as such
DYS389 I/II - Answer✔️✔️-one of 10 SWGDAM loci
- I and II loci "on top of" one another
- same mutational event as DYS385a/b, except not inverted
- defined as two loci that are close together
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