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NEUROMUSCULAR DISORDERS 2024 Questions & Answers Already Passed!!_.pdf
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8/31/24, 6:03 PMNEUROMUSCULAR DISORDERS
Jeremiah
ri_Bus
Terms in this set (28)
IV therapy that neutralizes autoantibodies and inhibits cytokine pathways.
IVIg
SE - fevers, chilld, HA, aseptic meningitis
Removing autoantibodies through a filter, requires IV line. SE include hypotension,
PLEX (Plasma Exchange)
paresthesias, delpleting coagulation factors, and requires a central line.
Prolonged use can lead to many SE so steroid sparing immunomodulary therapies are
Oral Corticosteroids
recommended but benefits aren't usually seen for 6+ months.
Dysfunction of the spinal cord r/t compression or lesion.
Gradual symptoms progress. May see weakness, hyperreflexia, and impaired sensation
below the level involved.
Cervical Myelopathy
Dx with imaging 0 MRI.
Tx surgery or tx underlying cause
Weakness, atrophy, fasciculations, and decreased reflexes below level of involvement.
Get EMG.
Diagnosis:
Anterior Horn Cell Disorders
ALS
Spinal Muscular Dystrophy
Spinal and bulbar musclar dystrophy
Poliomyelitis
Fatal, progressive disorder that affects the entire corticospinal tract, upper and lower
motor neurons. Unknown cause, familial connection.
Often presents after age 40.
Amyotrophic Lateral Sclerosis (ALS)
2 types
(1) Progressive muscular atrophy - isolated to lower motor neuron
(2) Primary lateral sclerosis - upper motor neuron dysfunction
Upper - weakness, spasticity, hyperreflexia
Upper vs Lower Motor Neuron Symptoms
NEUROMUSCULAR DISORDERS
Lower - weakness, atrophy, hyporeflexia
1/3
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