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Final Exam: NR546/ NR 546 (New 2024/ 2025 Update) Psychopharmacology for the PMHNP Complete Review (Weeks 5-8 Covered) -Questions and Verified Answers - 100% Correct-Grade A-Chamberlain $12.49
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Final Exam: NR546/ NR 546 (New 2024/ 2025 Update) Psychopharmacology for the PMHNP Complete Review (Weeks 5-8 Covered) -Questions and Verified Answers - 100% Correct-Grade A-Chamberlain

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Final Exam: NR546/ NR 546 (New 2024/ 2025 Update) Psychopharmacology for the PMHNP Complete Review (Weeks 5-8 Covered) -Questions and Verified Answers - 100% Correct-Grade A-Chamberlain

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Final Exam: NR546/ NR 546 (New 2024/ 2025
Update) Psychopharmacology for the
PMHNP Complete Review (Weeks 5-8
Covered) -Questions and Verified Answers -
100% Correct-Grade A-Chamberlain

QUESTION
IclientIeducationIforIspecificImedicationIclasses:ISSRI's
Answer:
MostIadverseIeffectsIwillIsubsideIafterI4-
5IdaysIonceItheIbodyIadjustsItoIincreasedIserotoninIlevels




QUESTION
IclientIeducationIforIspecificImedicationIclasses:ISNRI's
Answer:
-MedicationsIshouldInotIbeIabruptlyIstoppedItoIavoidIdiscontinuationIsymptoms.
-
NEIeffectsIofItheImedicationImayIincreaseIanxietyIinIsomeIclients.IReportIworseningIanxietyIt
oItheIprovider.




QUESTION
IclientIeducationIforIspecificImedicationIclasses:INDRI's
Answer:
-TakeImedicationIinItheImorning.
-StopItakingImedicationIifIseizuresIoccur.
-StopItakingImedicationIifIanxietyIisInoted.

,QUESTION
IOtherItxIoptions:ISARI's
Answer:
SerotoninIAntagonistIandIReuptakeIInhibitorsI
-potentlyIblockI5-HT2AIandI5HTI2CIreceptors,IallowImoreI5-
HTItoIinteractIatIpostsynapticI5-HT1AIsitesI
-TrazodoneImostIcommon
-adverseIeffects:
•Isedation
•Idrowsiness
•IblurredIvision
•Iconstipation
•IdryImouth
•Isevere:IpriapismI(MedicalIemergency)
PatientIeducation:IsideIeffects,ItakeIatIHSIdueItoIsedation
Off-labelIuses:Iinsomnia,Ianxiety




QUESTION
IOtherItxIoptions:ImiscellaneousIantidepressants
Answer:
MirtazapineI(Remeron)I
-SerotoninInorepinephrineIreceptorIagonist,Ialpha2IreceptorIagonist
-sedation/drowsiness,IusefulIforIclientsIwithIinsomnia.
-SideIeffects:IincreasedIappetite/weightIgain,IusefulIforIclientsIwithIdepression-
relatedIweightIloss

VilazodoneI(Viibryd)
-SerotoninImultimodalI(SMM)/serotoninIpartialIagonistIreuptakeIinhibitorI(SPARI)
-InhibitsIserotoninIreuptakeIwithIpartialI5HT1AIagonism
-
AppropriateIforIdepression/comorbidIanxiety,IactionIsimilarItoIcombinationIofISSRIIandIbuspi
rone.

VortioxetineI(Trintellix)
-SerotoninImultimodalI(SMM)
-ActsIasISSRIIplusI5HT1AIpartialIagonism

,-ImprovesIdepression-relatedIcognition




QUESTION
ITricyclicIantidepressants
Answer:
SRIIandINRIIproperties,IbutItheyIalsoIblockIα1-adrenergic,Ihistamine-
1,IandImuscarinicIcholinergicIreceptors
-notIusedIfirst-
lineIbecauseIofItheIhighIincidenceIofIadverseIeffectsIandItheIriskIofIpotentialIoverdoseIandIde
ath
•IamitriptylineI(Elavil)
•IdesipramineI(Norpramin)
•IdoxepinI(Sinequan)
•IimipramineI(Tofranil)
•InortriptylineI(Pamelor)




QUESTION
IAlpha-1IadrenergicIeffects
Answer:
OrthostaticIhypotension




QUESTION
IAnticholinergicIeffects
Answer:
DryImouth
BlurredIvision
UrinaryIretention
Constipation

, QUESTION
IHistamineIeffects
Answer:
WeightIgain
Sedation




QUESTION
IMAOIs
Answer:
firstIdeveloped,ILASTICHOICEImedicationIclassIforIdepressionIdueItoItheImanyIpotential,Iser
iousIsideIeffects
-
specificIdietaryIrestrictions,IFoodsIthatIcontainItyramineIshouldIbeIavoidedI(RedIwine,ISauerk
raut,ICheese,ISoy,ISmokedImeats)
-blockIenzymesIresponsibleIforItheIbreakdownIofI5-HT,INE,IandIDA
•ItwoIprimaryIformsIofItheIMAOIenzyme:IMAO-AIandIMAO-BI
•IbothIlocatedIinItheIbrain,IMAO-AIalsoIinIgut
Drugs:
-phenelzineI(Nardil)
-selegilineI(Emsam)I-IMAOI-B
-tranylcypromineI(Parnate)
-isocarboxazidI(Marplan)

SideIeffects:
-Confusion
-Dizziness
-Insomnia
-Sedation
-VividIdreams

Pearls:
-highIriskIforIhypertensiveIcrisisIifItyramineIisIingested
-
DoInotIprescribeIanyIserotonergicIagentsIwithinI2IweeksIofIMAOIIdiscontinuationIdueItoIanIi
ncreasedIriskIofIserotoninIsyndrome
-WaitIatIleastI5Ihalf-
livesIafterIdiscontinuingIaIserotonergicImedicationIbeforeIinitiatingIanIMAIO

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