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NAPLEX antibiotics Actual Exam Questions With Accurate Solutions Rated A+!!

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  • NAPLEX antibiotics
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  • NAPLEX Antibiotics

MIC - CORRECT ANSWER-lowest drug concentration that prevents visibile microbial growth in 24 hours gram (+) bacteria species - CORRECT ANSWER-staph, strep, EC, clostridium, listeria which antibiotics exhibit time-dependent killing? - CORRECT ANSWER-penicillins, cephalosporins how can you i...

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  • September 1, 2024
  • 26
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NAPLEX antibiotics
  • NAPLEX antibiotics
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NAPLEX antibiotics Actual Exam
Questions With Accurate Solutions
Rated A+!!

MIC - CORRECT ANSWER-lowest drug concentration that prevents visibile microbial
growth in 24 hours



gram (+) bacteria species - CORRECT ANSWER-staph, strep, EC, clostridium, listeria



which antibiotics exhibit time-dependent killing? - CORRECT ANSWER-penicillins,
cephalosporins



how can you increase the killing of a time-dependent antibiotic? - CORRECT ANSWER-
dose more frequently, extend the infusion time



example of concentration-dependent antibiotic? - CORRECT ANSWER-
aminoglycosides (gentamicin, tobramycin, amikacin)



what are the bacteriostatic antibiotics (protein synthesis inhibitors)? - CORRECT
ANSWER-macrolides

aminoglycosides

tetracyclines

clindamycin

linezolid

quinupristin, dalfopristin



what is the MOA of penicillins, cephalosporins, carbapenems, and vancomycin? -
CORRECT ANSWER-cell wall inhibitors - bactericidal

,what general ADRs are the black box warning for aminoglycosides? - CORRECT
ANSWER-nephrotoxicity and neurotoxicity



what are the aminoglycosides? - CORRECT ANSWER-tobramycin

gentamicin

amikacin



what type of nephrotoxicity do aminoglycosides cause? - CORRECT ANSWER-ATN -
acute tubular necrosis



what weight do you use to dose aminoglycosides? - CORRECT ANSWER-IBW (unless
TBW is less)

*use ABW if obese ( > 30% IBW)



what organisms are aminoglycosides mainly active against? - CORRECT ANSWER-
gram (-): GNR, PA



extended interval dosing of the aminoglycosides? - CORRECT ANSWER-gent/tobra: 4-
7 mg/kg

amikacin: 15-20 mg/kg

*draw random level within 6-16 hours after dose



adjust body weight (ABW) formula? - CORRECT ANSWER-IBW + [0.4(TBW - IBW)]



desired trough (traditional dosing) for gent/tobra? peak? - CORRECT ANSWER-trough:
< 2 mcg/mL

peak: 5-10 mcg/mL



amoxicilin brand name - CORRECT ANSWER-Amoxil

, what organisms do the penicillins cover? - CORRECT ANSWER-mainly gram (+), some
gram (-)



which penicillin is the DOC in acute otitis media? - CORRECT ANSWER-amoxicillin



which penicillin has activity against PA? - CORRECT ANSWER-piperacillin



which penicillins do not require renal dosing? - CORRECT ANSWER-nafcillin

oxacillin

dicloxacillin



Does Amoxil suspension need to be refrigerated? - CORRECT ANSWER-no - stable for
14 days at room temperature



how do you need to take Pen VK? - CORRECT ANSWER-on an empty stomach



what IV fluid is ampicillin only compatible with? - CORRECT ANSWER-NS



what are the main penicillin drug interactions? - CORRECT ANSWER-probenacid,
allopurinol - increased penicillin levels

may decrease levels of oral contraceptives



what type of killing do cephalosporins exhibit? - CORRECT ANSWER-time-dependent



what are the first generation cephalosporins? - CORRECT ANSWER-cefazolin and
cephalexin



what organisms are every cephalosporin active against? - CORRECT
ANSWER-strep/staph and GNR

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