ONCC PRACTICE TESTS (OCN - ONCOLOGIC
EMERGENCIES)
Which of the following cancers is associated with the development of disseminated
intravascular coagulation?
Mucin-secreting adenocarcinoma of the breast
Nonhyperdiploid variant multiple myeloma
Primary peritoneal carcinoma
Acral lentiginous melanoma - Answers -Mucin-secreting adenocarcinoma of the breast
Answer: The incidence of disseminated intravascular coagulation is associated mostly
with mucin-secreting adenocarcinomas of the prostate, lung, and breast.
Reference: Kaplan, M. (Ed.). (2013). Understanding and managing oncologic
emergencies: A resource for nurses (2nd ed.). Pittsburgh, PA: Oncology Nursing
Society, p. 69.
Which of the following is released into the bloodstream in the event of tumor lysis
syndrome?
Uric acid
Sodium
Magnesium
Calcium - Answers -Uric acid
Answer: Tumor lysis syndrome is a massive, sudden release of cellular contents in to
the bloodstream resulting in elevated uric acid levels.
Reference: Kaplan, M. (Ed.). (2013). Understanding and managing oncologic
emergencies: A resource for nurses (2nd ed.). Pittsburgh, PA: Oncology Nursing
Society, p. 440.
Which of the following classes of medication will most significantly increase the risk for
the development of a cytokine-release syndrome reaction?
Monoclonal antibodies
Taxanes
Platinum compounds
Anthracyclines - Answers -Monoclonal antibodies
Answer: Monoclonal antibodies can cause cytokine-release syndrome.
Reference: Newton, S., Hickey, M., & Marrs, J. (2017). Mosby's oncology nursing
advisor: A comprehensive guide to clinical practice (2nd ed.). St. Louis, MO: Elsevier
Mosby, p. 243.
, When a suspected extravasation occurs during the administration of a vesicant, the
nurse must first:
stop the administration of medication and fluids.
remove the peripheral IV or central venous access device.
aspirate the remaining vesicant from the IV tubing.
notify the healthcare provider. - Answers -stop the administration of medication and
fluids.
Answer: The first step the nurse should take when an extravasation occurs is stopping
the infusion.
Reference: Newton, S., Hickey, M., & Marrs, J. (2017). Mosby's oncology nursing
advisor: A comprehensive guide to clinical practice (2nd ed.). St. Louis, MO: Elsevier
Mosby, p. 217.
A dexrazoxane infusion shows efficacy for treating the extravasation of:
an anthracycline.
a nitrosourea.
an alkylating agent.
a plant alkaloid. - Answers -an anthracycline.
Answer: Dexrazoxane is the treatment for anthracycline extravasation.
Reference: Polovich, M., Olsen, M., & LeFebvre, K. (Eds.). (2014). Chemotherapy and
biotherapy guidelines and recommendations for practice (4th ed.). Pittsburgh, PA:
Oncology Nursing Society, p. 159(t).
A patient with sepsis reports hematuria and dyspnea. The laboratory values include
platelets 37,000/mm3, prothrombin time 21 seconds, partial thromboplastin time 43
seconds, and fibrinogen 100 mg/dL. Which of the following is the most likely cause?
Disseminated intravascular coagulation
Heparin-induced thrombocytopenia
Hemorrhagic cystitis
Idiopathic thrombocytopenic purpura - Answers -Disseminated intravascular
coagulation
Answer: Sepsis and infection can disrupt the clotting cascade, causing disseminated
intravascular coagulation.
Reference: Newton, S., Hickey, M., & Marrs, J. (2017). Mosby's oncology nursing
advisor: A comprehensive guide to clinical practice (2nd ed.). St. Louis, MO: Elsevier,
pp. 381-382.