CHAPTER 2: FUNCTIONAL
NEUROANATOMY: THE NERVOUS
SYSTEM AND BEHAVIOR
u Neuron (Nerve Cell) - The basic unit of the nervous system, each composed of receptive extensions
called dendrites, an integrating cell body, a conducting axon, and a transmitting axon terminal
Glial Cells (Glia, Neuroglia) - Nonneuronal brain cells that provide structural, nutritional, and other types
of support to the brain
Neuron Doctrine - The hypothesis that the brain is composed of separate cells that are distinct
structurally, metabolically, and functionally
Synapse - The tiny gap between neurons where information is passed from one to the other
Mitochondrion - A cellular organelle that provides metabolic energy for the cell's processes
Cell Nucleus - The spherical central structure of a cell that contains the chromosomes
Ribosomes - Structures in the cell body where genetic information is translated to produce proteins
Dendrite - One of the extensions of the cell body that are the receptive surfaces of the neuron
Input Zone - The part of a neuron that receives information from other neurons or from specialized
sensory structures; usually corresponds to the cell's dendrites
Cell Body (Soma) - The region of a neuron that is defined by the presence of the cell nucleus
Integration Zone - The part of the neuron that initiates nerve electrical activity; usually corresponds to
the neuron's axon hillock
Axon - A single extension from the nerve cell that carries action potentials fro the cell body to other
neurons
Conduction Zone - The part of the neuron over which the nerve's electrical signal may be actively
propagated; usually corresponds to the cell's axon
Axon Collateral - A branch of an axon from a single neuron
Axon Terminal (Synaptic Button) - The end of an axon or axon collateral, which forms a synapse on a
neuron or other target cell
Output Zone - The part of a neuron, usually corresponding to the axon terminals, at which the cell sends
information to another cell
Multipolar Neuron - A nerve cell that has many dendrites and a single axon
Bipolar Neuron - A nerve cell that has a single dendrite at one end and a single axon at the other end
, Unipolar (Monopolar) Neuron - A nerve cell with a single branch that leaves the cell body and then
extends in two directions; one end is the receptive pole, and the other end is the output end
Motor Neuron (Motoneuron) - A nerve cell that transmits motor messages, stimulating a muscle or gland
Sensory Neuron - A neuron that is directly affected by changes in the environment, such as light, odor, or
touch
Interneuron - A neuron that is neither a sensory neuron nor a motor neuron; it receives input from and
sends output to other neurons
Arborization - The elaborate branching of the dendrites of some neurons
Presynaptic - Referring to the region of a synapse that releases neurotransmitter
Postsynaptic - Referring to the region of a synapse that receives and responds to neurotransmitter
Presynaptic Membrane - The specialized membrane of the axon terminal of the neuron that transmits
information by releasing neurotransmitter
Synaptic Cleft - The space between the presynaptic and postsynaptic elements
Postsynaptic Membrane - The specialized membrane on the surface of the cell that receives information
by responding to neurotransmitter from a presynaptic neuron
Synaptic Vesicle - A small, spherical structure that contains molecules of neurotransmitter
Neurotransmitter (Synaptic Transmitter, Chemical Transmitter, Transmitter) - The chemical released from
the presynaptic axon terminal that serves as the basis of communication between neurons
Histology - The scientific study of the composition of tissue
Nissl Stain - A cell stain that revels all cell bodies by staining RNA
Golgi Stain - A cell stain that fills a small proportion of neurons with a dense dark product
Autoradiography - A histological technique that hows the distribution of radioactive chemicals in tissues
Immunohistochemistry (IHC) - A technique in which labeled antibodies are used to visualize the
histological distribution of specific proteins
In Situ Hybridization - A technique in which labeled complementary nucleic probes are used to identify
cells expressing specific messenger RNA transcripts, reflecting the activation of specific genes of interest
Tract Tracer - A compound used to identify the routes and interconnections of neuronal projections
Receptor (Receptor Molecule) - A protein that binds and reacts to molecules of a neurotransmitter or
hormone
Neural Plasticity (Neuroplasticity) - The ability of the nervous system to change in response to experience
or the environment
Axon Hillock - A cone-shaped area from which the axon originates out of the cell body; functionally, the
integration zone of the neuron
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