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NURS 251 Module 10 – Pharmacology/ Q&A/ .

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NURS 251 Module 10 – Pharmacology/ Q&A/ . Terms like: lithium MOA - Answer: alters ion transport in nerve and muscle cells and increases receptor sensitivity to serotonin lithium interactions - Answer: increased levels with diuretics, methyldopa, NSAIDs, haloperidol, antidepressants, theop...

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  • September 3, 2024
  • 10
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • NURS 251
  • NURS 251

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NURS 251 Module 10 – Pharmacology/ Q&A/
2024-2025.
lithium MOA - Answer: alters ion transport in nerve and muscle cells and
increases receptor sensitivity to serotonin


lithium interactions - Answer: increased levels with diuretics, methyldopa, NSAIDs,
haloperidol, antidepressants, theophylline, phenothiazole


lithium therapeutic range - Answer: 0.5-1.5


lithium adverse effects - Answer: headache, drowsiness, dizziness, hypotension,
restlessness, slurred speech, metallic taste, dry mouth, GI distress, tremors,
muscle weakness, hand/ankle edema, increased urination, blood dyscarias


lithium toxicity s/s - Answer: nausea, vomiting, diarrhea, slurred speech, increased
tremors, seizures, coma, decreased coordination

, lithium nursing considerations - Answer: - monitor kidney function
- monitor for low Na (<145)
- suicidal thoughts
- increase fluid intake
- avoid caffeine
- take w food to minimize GI upset


amitriptyline, nortriptyline indications - Answer: major/agitated depression


amitriptyline, nortriptyline MOA - Answer: blocks norepinephrine + serotonin
uptake in the brain + blocks histamine receptors


amitriptyline, nortriptyline contraindications - Answer: MAOIs (14 days),
pregnancy, pt with chronic cardiac/seizure disorders


amitriptyline, nortriptyline interactions - Answer: - cns dep. + alcohol - increased
cns effects
- MAOIs - cardiotoxicity
- phenothiazine, haloperidol - increased sedation + anticholinergic effects


amitriptyline, nortriptyline adverse effects - Answer: sedation, dizziness,
anticholinergic, weight gain, GI distress, sexual dysfunction, orthostatic
hypotension, dysrhythmias, blood dyscarias

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