The major functions of the spleen can be divided into two general
categories of hematologic and immunologic functions. Which of the
following statements is true regarding the normal function of the
spleen?
Give this one a try later!
The primary hematologic
The spleen provides the function of the spleen is
environment for generation of the removal of senescent red
, humoral but not cellular aspects of blood cells or remodeling of
the normal immune response. abnormal red cells with
various deformities.
Throughout a normal lifetime, the
Destruction of platelets and
spleen continues to serve as an
leukocytes is an important normal
important secondary source of
physiologic function of the spleen.
hematopoiesis for all cell types.
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2 of 22
Term
A 35-year-old female is referred by her primary care physician after
reporting an increase in bleeding during her last 3 menstrual cycles
and a tendency to bruise easily. She denies taking any medications,
or using tobacco or recreational drugs. She has platelet count of
40,000 and demonstrates oral mucosal bleeding. You suspect she
has immune thrombocytopenic purpura (ITP). What do you
recommend for treatment?
Give this one a try later!
Splenectomy Platelet transfusion
Intravenous gamma-
Corticosteroids
immunoglobulin
, Romiplostim (an agonist for
thrombopoietin receptor)
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3 of 22
Term
You are consulted on a 55-year-old homeless woman admitted for
sepsis with documented gram-positive bacteremia. A CT scan of the
abdomen obtained today is shown below (multifocal abscesses). She
has been started on broad-spectrum antibiotics. What is the most
appropriate next step in her management?
Give this one a try later!
Mesenteric angiography and Image-guided percutaneous drain
embolization placement
Fine needle aspiration and culture
Splenectomy
of splenic lesions
Administration of IgG
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4 of 22
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