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NR 566 Pharm final Questions & Answers(GRADED A+)

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Doxazosin side effects - ANSWER orthostatic hypotension, falls, reflex tachycardia, headache, and nasal congestion Dutasteride patient teaching and response to delayed onset of therapeutic effect - ANSWER o benefits take months to develop o decreased ejaculate volume and libido. o FDA Pregna...

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  • September 4, 2024
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  • Exam (elaborations)
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  • NR 566 Pharm f
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NR 566 Pharm final Questions
& Answers(GRADED A+)
Doxazosin side effects - ANSWER orthostatic hypotension, falls, reflex tachycardia, headache, and
nasal congestion



Dutasteride patient teaching and response to delayed onset of therapeutic effect - ANSWER o
benefits take months to develop

o decreased ejaculate volume and libido.

o FDA Pregnancy Risk Category X. It can be absorbed through the skin, so pregnant women should
not handle the drug.

o men should not donate blood while using it or for at least 6 months after stopping it to avoid
transmission to women through an infusion



How to know Terazosin is working - ANSWER improved symptoms of dysuria, urgency, urinary tract
infections, hesitancy



Various routes of administration of estrogen therapy and when each would be used - ANSWER o PO
—used more than any other

o Compared with oral formulations, the transdermal formulations have four advantages:

• The total dose of estrogen is greatly reduced (because the liver is bypassed).

• There is less nausea and vomiting.

• Blood levels of estrogen fluctuate less.

• There is a lower risk for DVT, pulmonary embolism, and stroke

o Intravaginal administration—available as tablets, creams, and vaginal rings. They are used only for
local effects, primarily treatment of vulval and vaginal atrophy associated with menopause. The
other vaginal ring [Femring] can also help with systemic effects (i.e. control of hot flashes and night
sweats)

o IV and IM—limited to acute, emergency control of heavy uterine bleeding

, When is it safe and not safe to prescribe progesterone (AKA: progestin) - ANSWER o Safe—
menopausal hormone therapy, dysfunctional uterine bleeding, amenorrhea, endometrial cacer and
hyperplasia

o Not safe—arterial disease, breast cancer, depression



Side effects of progestin-only oral contraceptives - ANSWER o more likely to cause
irregular/inconsistent bleeding

o must be taken at same time every day to be effective



Benefits of prescribing medroxyprogesterone acetate - ANSWER protects against pregnancy for 3
months or longer



Patient teaching in general and consider teaching specific to different routes of testosterone therapy
- ANSWER § GELS

· good hand washing is required after application

· cover application site with clothing after medication has dried

· females and children may experience negative effects from exposure to testosterone

§ PILLS

· Pose a risk for hepatotoxicity, so do not take long term

§ PATCH

· Principal adverse effect is rash at the site of application

§ IM

· Cause variations in libido, energy, mood



When is androgen therapy appropriate vs. not needed related to puberty? - ANSWER Appropriate
when the psychological pressures of delayed sexual maturation are causing a boy significant distress
or if delayed puberty is related to true hypogonadism



Common side effects of androgen therapy - ANSWER Hot flashes, bone fractures, decreased libido,
insulin resistance, erectile dysfunction, gynecomastia, acne, HTN, sterility, hepatotoxicity, mood
swings/ aggression



alprostadil benefits of various routes - ANSWER o injection: can be done by patient or in ER setting;
rapidly leads to erection, painless

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