-Age, pregnancy and lactation, recent antibiotic use, exposure history (wt based dosing for pediatric
and geriatric population)
*The SYNDROME or PRESENTING ILLNESS
-what system is impacted
-how aggressive the infection
-consider non-bacterial causes
-carefully examine clinical presentation of illness
*The PATHOGEN
-obtaining culture and sensitivity/resistance
-how susceptibility is determined
AST/Petri dish growth
commonly used for empiric therapy when the pathogen is unknown or infection with multiple types
of bacteria and suspected
Risks of using broad-spectrum antibiotics - ANSWER Disruption of normal flora and development of
anabiotic resistance
Therapeutic trials class used for CAP - ANSWER Amoxicillin doxycycline macrolides
Likely prescription for a CAP - ANSWER Amoxicillin PO for 7 to 10 days or azithromycin PO for five
days
Tx for severe CAP - ANSWER Beta-lactam and macrolide or fluroquinolone
Likely prescription for severe CAP - ANSWER Ampicillin/sulbactam IV and azithromycin IV or
levofloxacin IV x 5 days
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