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BIPN 102 Midterm 2 Questions And Answers With Latest Quiz $7.99   Add to cart

Exam (elaborations)

BIPN 102 Midterm 2 Questions And Answers With Latest Quiz

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  • BIPN 102
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  • BIPN 102

emphysema and fick's equation - airway obstruction as a result of inorganic particles --> triggers the production of elastase which breaks down elastin --> alveoli lose elastance --> alveoli recoil --> increase in T and decrease in A --> lower gas exchange inspired partial pressur...

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  • September 5, 2024
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  • 2024/2025
  • Exam (elaborations)
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  • BIPN 102
  • BIPN 102
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PatrickKaylian
BIPN 102 Midterm 2
emphysema and fick's equation - airway obstruction as a result of inorganic particles --> triggers
the production of elastase which breaks down elastin --> alveoli lose elastance --> alveoli recoil -->
increase in T and decrease in A --> lower gas exchange



inspired partial pressure - Pi,o2 = Fo2 * (Patm - Ph2o)

air conditioning during inhalation: adds warmth and moisture to the gas --> water gets evaporated in the
mucosa, generating a water pressure which decreases the atmospheric pressure

at 37C, Ph2o= 47 mmHg

dalton's law - Pair = Po2 + Pn2 + Pco2 + Par



henry's law - C = alphaP

the concentration/amount of a dissolved gas is a function of the gas's Pp and solubility coefficient



partial pressure calculation - Pgas = Fgas * Patm




alveolar partial pressure - PA = Pi,o2 - Po2 = 150 mmHg - 50 mmHg = 100 mmHg

Pi,o2 = Fo2 * (Patm-Ph2o) = .21(760-47) = 150 mmHg

Po2 = Pa,co2/RQ = 40 mmHg/0.8 = 50 mmHg



how much oxygen is diffusing out of the alveoli



fick's equation - V = ((PA-Pb)*A*D/)T OR V/A = ((PA-Pb)*D/)T

V = flow rate

PA-Pb = pressure gradient

A = surface area

D = diffusion coefficient

, T = thickness/distance

V/A = net rate of particles moving through A; flux

(PA-Pb)/T = change in P over a distance

D*A/T = diffusion capacity, D(L)



fibrosis and fick's equation - smoke cannot be destroyed by macrophages --> production of
collagen --> collagen/scar tissue on the alveoli --> increase in T --> decrease in gas exchange



edema and fick's equation - swelling and increased fluid in the interstitial space --> increase in T
(greater diffusion distance) --> decrease in gas exchange



asthma and fick's equation - hyper responsiveness/sensitivity of the airways --> airway
obstruction, swelling, mucus, etc --> increase in T --> decrease in gas exchange




perfusion limited gas exchange - - gas exchange is limited by the blood flow rate through the
capillaries

- the pressure in the capillaries and alveoli equilibrate quickly, usually within 1/3 of transportation time

- diffusion can happen effectively and the limiting factor is how fast the blood is moving through the
capillary and how much hemoglobin we have that binds to the blood

- normal with oxygen



pulmonary circulation resistance and pressure change - - increase in pulmonary pressure
decreases pulmonary resistance

- capillaries can collapse at low pressures/blood flow --> when pressure is increased, they are recruited
(open up) --> continued increases in pressure cause capillary distention (even more dilation) --> as a
result, more pathways are opened and resistance decreases



ventilation/perfusion ratios - V/Q = 1

- ventilation and perfusion are matched

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