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NR 546 Exam with correct answers
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NR 546 Exam with correct answersPrefrontal |Cortex |Symptoms |of |MDD |- |correct |answer-Concentration
Mental |Fatigue
Mood
PFC |& |Amygdala |Symptoms |of |MDD |- |correct |answer-Guilt
Suicidality
Worthlessness
Striatum |Symptoms |of |MDD |- |correct |answer-Physical |fatigue
Nucleus |Accumbens |Symptoms |of |MDD |- |correct |answer-Pleasure |interests
Hypothalamus |Symptoms |of |MDD |- |correct |answer-Sleep
Appetite
Thalamus |& |Hypothalamus |Symptoms |of |Mania |- |correct |answer-Decreased |sleep/arousal
Striatum |Symptoms |of |Mania |- |correct |answer-Motor/agitation
Prefrontal |cortex |(PFC) |Symptoms |of |Mania |- |correct |answer-Risk-taking
Talkative/pressured |speech
Nucleus |Accumbens |& |PFC |Symptoms |of |Mania |- |correct |answer-Racing |thoughts, |
grandiosity
,PFC |& |Amygdala |Symptoms |of |Mania |- |correct |answer-Mood
Medication |Management |- |correct |answer-SSRI-Selective |Serotonin |Reuptake |Inhibitors
*Inhibit |5 |HT |reuptake
SNRI-Serotonin |Norepinephrine |Reuptake |Inhibitors |
*inhibit |5-HT |reuptake
*inhibit |NE |reuptake |(increase |energy, |focus)
*increase |DA |in |prefrontal |cortex |(increase |cognition)
NDRI-Norepinephrine |Dopamine |Reuptake |inhibitors
*inhibit |DA |reuptake |(increase |alertness, |motivation)
*inhibit |NE |reuptake |(increase |energy)
SARI-Serotonin |Antagonist |Reuptake |Inhibitors
Selective |Serotonin |Reuptake |Inhibitors |(SSRIs): |Most |adverse |effects |will |subside |after |4-5 |
days |once |the |body |adjusts |to |increased |serotonin |levels. |- |correct |answer-diarrhea
headache
weight |gain
sexual |side |effects
Serotonin |Norepinephrine |Reuptake |Inhibitors |(SNRIs): |Medications |should |not |be |abruptly |
stopped |to |avoid |discontinuation |symptoms. |NE |effects |of |the |medication |may |increase |
anxiety |in |some |clients. |Report |worsening |anxiety |to |the |provider. |- |correct |answer-elevated |
blood |pressure
anxiety
insomnia
constipation
,Norepinephrine |Dopamine |Reuptake |Inhibitors |(NDRI): |Take |medication |in |the |morning. |
Stop |taking |medication |if |seizures |occur. |Stop |taking |medication |if |anxiety |is |noted. |- |correct |
answer-agitation
headache
dry |mouth
constipation
weight |loss
escitalopram |(Lexapro) |SSRI |- |correct |answer-no |known |drug |interactions
best |tolerated |SSRI
27-32 |hour |half-life |good |for |forgetful |prone |clients
least |CYP |reactions
Substrate |for |3A4
citalopram |(Celexa) |SSRI |- |correct |answer-mild |antihistamine |effects; |Half-Life: |23-45 |hours
Weak |Inhibitor |of |2D6
fluoxetine |(Prozac) |SSRI |- |correct |answer-longest |half-life
Use |caution |in |patients |with |comorbid |anxiety |due |to |risk |for |activation |and |panic |attacks
Half-Life: |2-3 |days |parent, |2 |week |metabolite
Inhibits |2D6 |and |3A4
paroxetine |(Paxil) |SSRI |- |correct |answer-also |treats |social |anxiety |and |insomnia
associated |with |weight |gain
will |experience |withdrawal |with |missed |dose |or |abrupt |stop
Half-Life: |24 |hours
Inhibits |2D6
, fluvoxamine |(Luvox) |SSRI |- |correct |answer-treats |anxious |depression |smokers |require |an |
increased |dose
Half-Life: |9-28 |hours
Inhibits |3A4, |2C9, |1A2
sertraline |(Zoloft) |SSRI |- |correct |answer-also |treats |social |anxiety |and |hypersomnolence
Half-Life: |22-36 |hour |parent; |62-104 |hour |metabolite
Inhibits |2D6 |and |3A4 |weakly |at |low |doses
venlafaxine |(Effexor) |- |correct |answer-treats |both |depression |and |anxiety |disorders, |ensure |
trial |of |higher |dose |before |switching |to |a |different |medication
Half-life: |Parent |drug |3-7 |hour; |metabolite |has |9-13 |hour
duloxetine |(Cymbalta) |SNRI |- |correct |answer-effective |for |atypical |pain |at |higher |doses; |
appropriate |for |clients |who |present |with |somatic |symptoms |of |depression; |effective |for |
atypical |pain, |such |as |fibromyalgia |and |diabetic |neuropathy
Half-Life: |12 |hours
Inhibitor |of |2D6
bupropion |(Wellbutrin) |- |correct |answer-NDRI |may |improve |energy, |alertness, |and |
motivation; |not |first-line |treatment |for |anxiety; |contraindicated |in |clients |with |a |history |of |
seizures
Avoid |in |patients |with |comorbid |anxiety
Half-Life: |Parent |10-14 |hours; |Metabolite |20-27 |hours
Inhibits |2D6
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