Bio Final 2 Questions
Cytokines - Proteins that attract more WBCs, including monocytes
Pathogens - Agents that cause infectious disease, such as bacteria, viruses, fungi, protists, worms,
and other parasites
Macrophages - Are more powerful phagocytes than neutrophils
What the immune system can determine - Self from nonself
Autoimmune diseases - Result from the immune system attacking an animal's own cells as if they are
a pathogen
Immunodeficiency - Results from the immune system not recognizing pathogens as notself
Innate immunity - Provides protection against all forms of infection in a non-specific manner; does
not depend on previous exposure
Adaptive immunity - Specific to a given pathogen; results from exposure to that specific pathogen
Physical and chemical barriers - Skin, Skin microbiome, and Mucus membranes/secretions / tears
Inflammatory response - Employs neutrophils and macrophages to surround and kill invading
pathogens
Histamine - A chemical mediator released by damaged tissue cells and mast cells which cause the
capillaries to dilate and become more permeable
If neutrophils are overwhelmed they release - Cytokines
Complement system - Composed by a number of blood plasma proteins that increase the immune
response of one or more specific immune responses
,Complement proteins can - -Trigger mast cells to release histamine
-Attract phagocytes to a specific location
-Bind directly to bacteria can cause them to burst
interferons - Proteins produced by virus-infected cells that cause uninfected cells to prepare for viral
infection by producing substances that interfere with viral replication
Antigen - A large protein structure that the immune system recognizes as a foreign body
Adaptive defenses primarily depend on... - B and T cells (B and T lymphocytes)
Each lymphocyte has a single kind of receptor to combine with a... - A specific antigen (like a lock and
key)
Adaptive immunity pathways have 2 types of immunity - •Cell-mediated immunity
•Antibody-mediated (humoral) immunity
Cell-mediated immunity - T-cells target and destroy any cells that present a specific antigen
Helper t cells - May come into contact with an antigen and release cytokines to call Cytotoxic T cells
to the area
Cytotoxic T cells - Either phagocytize or trigger apoptosis in infected cells
An antigen binds with a... - B cell's receptor
The B cell then undergoes rapid clonal expansion which creates... - B memory cells, and plasma cells
The plasma cells created and secrete what for the original antigen? - Antibodies
This cell is the only one that has receptors that fit the antigen that undergo clonal expansion - Only
the B cells
, Antibody structure (y) - Shaped with two antigen binding sites
Antibody function - Many antibodies will bind with the antigens, covering the offending molecule so
that it can't bind
Monocytes - Longer-lived cells that become Macrophages
Cytotoxic t cells - Specialized T lymphocytes with storage vacuoles that contain perforins and storage
vacuoles that contain granzymes (an enzyme that causes apoptosis)
Helper t cells - Specialized T lymphocytes that regulate immunity by secreting cytokines
B lymphocytes cannot be activated without... - T cell help
HIV does what to t cells - Attacks T cells, which leaves patients vulnerable to opportunistic
Memory t cells - Remain within the body and can jump-start an immune response to an antigen
previously present in the body
Immunization - Involves the use of vaccines to expose the immune system to the antigen
Vaccine - Substances that contain an antigen to which the immune system responds
Chemosensory - taste and smell
Electromagnetic receptor - sight
Mechanoreceptor - Touch, Hearing and balance
What sensory receptor cells rely on - Rely on membrane receptors
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